Intracerebroventricular injection of muscimol, baclofen or nipecotic acid stimulates food intake in layer-type, but not meat-type, chicks

Takashi Bungo, Tomofumi Izumi, Kazuya Kawamura, Tomo Takagi, Hiroshi Ueda, Mitsuhiro Furuse

研究成果: ジャーナルへの寄稿学術誌査読

28 被引用数 (Scopus)

抄録

This study was designed to compare the effects of muscimol (GABA A agonist), baclofen (GABAB agonist) and nipecotic acid (GABA uptake inhibitor) on food intake in two chicken strains (meat-type and layer-type chicks). The intracerebroventricular (ICV) injection of all GABA agents induced hyperphagia in layer-type chicks. However, in broiler chicks, there were similar tendencies with muscimol and nipecotic acid but not significantly different. Conversely, ICV injection of baclofen depressed feeding of broiler chicks. These results suggest that there are some differences in central GABAergic systems between these strains of chicks, but GABAergic systems have an important role in the regulation of food intake in neonatal chicks.

本文言語英語
ページ(範囲)235-238
ページ数4
ジャーナルBrain Research
993
1-2
DOI
出版ステータス出版済み - 12月 12 2003

!!!All Science Journal Classification (ASJC) codes

  • 神経科学(全般)
  • 分子生物学
  • 臨床神経学
  • 発生生物学

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