Intraductal carcinoma in a surgically resected pancreas with chronic pancreatitis

Kazuhiro Mizumoto, Masahiro Tsutsumi, Shunji Kitazawa, Shigenobu Tsujita, Masaki Nakayama, Tadasu Tsujii, Hiromichi Kanehiro, Yoshiyuki Nakajima, Hiroshige Nakano, Yoichi Konishi

研究成果: ジャーナルへの寄稿学術誌査読


A 59-yr-old Japanese male presented with epigastralgia. Endoscopic retrograde cholangiopancreatography (ERCP) revealed narrowing of the inferior common bile duct and protein plugs in the main pancreatic duct. He was diagnosed as suffering from chronic pancreatitis with suspicion of a pancreatic head tumor, and a pancreatoduodenectomy was performed. Histologically, a diffuse chronic pancreatitis was evident in the resected pancreas. Although no tumors were seen in the head portion of the pancreas around the inferior common bile duct, an intraductal carcinoma was found in the second branch of Santorini's duct. Precancerous alteration of the duct epithelium, presenting papillary hyperplasia, and atypical hyperplasia were observed in areas continuous with the intraductal carcinoma. Immunohistochemically, carcinoembronic antigen (CEA) was specifically expressed in atypical hyperplasia and intraductal carcinoma, but not in papillary hyperplasia.

ジャーナルInternational Journal of Pancreatology
出版ステータス出版済み - 12月 1990

!!!All Science Journal Classification (ASJC) codes

  • 腫瘍学
  • 内分泌学
  • 消化器病学


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