Intravascular lymphoma confirmed by brain biopsy, quickly treated by chemotherapy: A case report

Daisuke Inoue, Takeshi Hamamura, Taira Uehara, Katsue Miyoshi, Takefumi Katsuragi, Iwao Takeshita, Tetsuo Hamada

研究成果: Contribution to journalArticle査読

2 被引用数 (Scopus)

抄録

A 60-year-old female with intravascular lymphoma (IVU presented with the complaint of urinary dysfunction and gait disturbance. T2 weighted MR imaging of the thoracic spinal cord showed a hyperintense lesion, and brain MR imaging indicated hyperintense lesions in the deep white matter. Multiple sclerosis was assumed, so steroid pulse therapy was administered. However, her level of consciousness decreased and her paraplegia progressed. Laboratory data showed that anemia and thrombocytopenia had worsened with high serum LDH and soluble (L-2 receptor levels. Biopsy of bone marrow indicated rryperceHularity associated with hemophagocytic histiocytes, although no atypical lymphocytes were detected. Sraln MR imaging Indicated a new subcortical lesion in the left parietal lobe. One and a half months after admission, an open brain biopsy of the left parietal cortex was performed. Hlstopathological diagnosis was IVL, large B cell type. Immediately, she underwent CHOP therapy containing rituximab (R-CHOP therapy). After chemotherapy, spinal and brain MR Images showed no new abnormal lesions. Clinically, It Is difficult to make a diagnosis of IVL in life as It has no characteristic symptoms or radiological findings. Therefore, if a patient is suspected of having IVL, a biopsy of different organs, including brain, is necessary for making an early diagnosis and Initiating chemotherapy.

本文言語英語
ページ(範囲)369-374
ページ数6
ジャーナルNeurological Surgery
37
4
出版ステータス出版済み - 4 2009

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

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