抄録
Background: It is clinically necessary to validate a new non-invasive and reliable imaging method to detect early chronic pancreatitis. Intravoxel incoherent motion magnetic resonance imaging (MRI) is useful for quantitative assessment in abdominal solid organs. Purpose: To investigate the usefulness of intravoxel incoherent motion MRI parameters in the diagnosis of chronic pancreatitis. Material and Methods: Sixty patients with early chronic pancreatitis (n = 44) and chronic pancreatitis (n = 16) were assessed with intravoxel incoherent motion imaging. For comparison, a control group of 71 individuals without chronic pancreatitis was also enrolled. The perfusion fraction (f), pseudo-diffusion coefficient (D*), true diffusion coefficient (D), and apparent diffusion coefficient of pancreatic parenchyma were calculated. These measurements were compared between the three groups. The diagnostic accuracy of imaging parameters was assessed. Results: The f values of the early chronic pancreatitis group and the chronic pancreatitis group were significantly lower than those of the control group (P < 0.001 and P < 0.001, respectively). The D* value of the chronic pancreatitis group was significantly lower than that of the early chronic pancreatitis group (P = 0.0025). The D values of the early chronic pancreatitis group and the chronic pancreatitis group were significantly higher than those of the control group (P = 0.001 and P = 0.001, respectively). The perfusion fraction showed the highest diagnostic performance with an Az value of 0.76 for discriminating the control group from the early chronic pancreatitis and chronic pancreatitis groups. Conclusion: Intravoxel incoherent motion MRI parameters may reflect the minimal histological changes in early chronic pancreatitis.
本文言語 | 英語 |
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ページ(範囲) | 579-585 |
ページ数 | 7 |
ジャーナル | Acta Radiologica |
巻 | 61 |
号 | 5 |
DOI | |
出版ステータス | 出版済み - 5 1 2020 |
All Science Journal Classification (ASJC) codes
- Radiological and Ultrasound Technology
- Radiology Nuclear Medicine and imaging