超常磁性酸化鉄ナノパーティクル表面への蛍光性物質の導入と放出反応の検討

秋田 健行, 古賀 登

研究成果: Contribution to journalArticle

抄録

Chemical introduction and release of fluorescent chromophores on a surface of Super-Paramagnetic Iron Oxide Nanoparticles (SPION) were investigated. An aqueous solution of SPION having carboxylic acid and poly(ethylene glycol) groups on its surface was prepared by a reported method. A fluorescent chromophore, a derivative of fluorescein attached with aminobutenyl ether, was introduced into the SPION surface through amide bond by using of EDC. An emission of the fluorescein was quenched by introduction of the aminobutenyl ether, and the SPION solution introduced by the fluorescein derivative exhibited only weak fluorescence at ~510 nm. Once Pd(PPh<SUB>3</SUB>)<SUB>4</SUB> was added to the solution, butenyl ether bond was cleaved and release of free fluorescein was observed by increase of emission at 510 nm. This release reaction was also revealed by NMR and UV spectra of model compounds.
寄稿の翻訳タイトルIntroduction and Release of Fluorescent Chromophores on a Surface of Suoer-paramagnetic Iron Oxide Nanoparticles (SPION)
本文言語日本語
ページ(範囲)466-466
ページ数1
ジャーナル基礎有機化学討論会要旨集(基礎有機化学連合討論会予稿集)
2011
0
DOI
出版ステータス出版済み - 2011

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