抄録
The development of effective methods to disinfect biofilms on dental materials is medically important. This study evaluated the bactericidal effects of peroxynitric acid (HOONO2; PNA) on biofilms formed on titanium surfaces. Streptococcus gordonii was cultured on either machined or rough titanium discs that were then used to evaluate the bactericidal effects of seven reagents, i.e., normal saline, benzalkonium chloride disinfectant solution, chlorhexidine digluconate solution, three concentration types of PNA, and inactivated PNA. Using low concentration of PNA, the bacterial count based on a CFU assay reached an undetectable level within 10 s; this bactericidal effect was the strongest observed for the seven tested reagents. Thus, PNA may be more useful than other disinfectants for sterilizing biofilms on titanium surfaces that have been contaminated with bacteria.
| 元の言語 | 英語 |
|---|---|
| ページ（範囲） | 654-662 |
| ページ数 | 9 |
| ジャーナル | dental materials journal |
| 巻 | 38 |
| 発行部数 | 4 |
| DOI | |
| 出版物ステータス | 出版済み - 1 1 2019 |
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All Science Journal Classification (ASJC) codes
- Ceramics and Composites
- Dentistry(all)
これを引用
Investigation of a novel sterilization method for biofilms formed on titanium surfaces. / Nagao, Rei; Esaki, Daisuke; Shibata, Yukie; Ikawa, Satoshi; Kitano, Katsuhisa; Ayukawa, Yasunori; Matsushita, Yasuyuki; Takeshita, Toru; Yamashita, Yoshihisa; Matsuzaki, Masaaki; Koyano, Kiyoshi.
：: dental materials journal, 巻 38, 番号 4, 01.01.2019, p. 654-662.研究成果: ジャーナルへの寄稿 › 記事
}
TY - JOUR
T1 - Investigation of a novel sterilization method for biofilms formed on titanium surfaces
AU - Nagao, Rei
AU - Esaki, Daisuke
AU - Shibata, Yukie
AU - Ikawa, Satoshi
AU - Kitano, Katsuhisa
AU - Ayukawa, Yasunori
AU - Matsushita, Yasuyuki
AU - Takeshita, Toru
AU - Yamashita, Yoshihisa
AU - Matsuzaki, Masaaki
AU - Koyano, Kiyoshi
PY - 2019/1/1
Y1 - 2019/1/1
N2 - The development of effective methods to disinfect biofilms on dental materials is medically important. This study evaluated the bactericidal effects of peroxynitric acid (HOONO2; PNA) on biofilms formed on titanium surfaces. Streptococcus gordonii was cultured on either machined or rough titanium discs that were then used to evaluate the bactericidal effects of seven reagents, i.e., normal saline, benzalkonium chloride disinfectant solution, chlorhexidine digluconate solution, three concentration types of PNA, and inactivated PNA. Using low concentration of PNA, the bacterial count based on a CFU assay reached an undetectable level within 10 s; this bactericidal effect was the strongest observed for the seven tested reagents. Thus, PNA may be more useful than other disinfectants for sterilizing biofilms on titanium surfaces that have been contaminated with bacteria.
AB - The development of effective methods to disinfect biofilms on dental materials is medically important. This study evaluated the bactericidal effects of peroxynitric acid (HOONO2; PNA) on biofilms formed on titanium surfaces. Streptococcus gordonii was cultured on either machined or rough titanium discs that were then used to evaluate the bactericidal effects of seven reagents, i.e., normal saline, benzalkonium chloride disinfectant solution, chlorhexidine digluconate solution, three concentration types of PNA, and inactivated PNA. Using low concentration of PNA, the bacterial count based on a CFU assay reached an undetectable level within 10 s; this bactericidal effect was the strongest observed for the seven tested reagents. Thus, PNA may be more useful than other disinfectants for sterilizing biofilms on titanium surfaces that have been contaminated with bacteria.
UR - http://www.scopus.com/inward/record.url?scp=85070851257&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85070851257&partnerID=8YFLogxK
U2 - 10.4012/dmj.2018-274
DO - 10.4012/dmj.2018-274
M3 - Article
VL - 38
SP - 654
EP - 662
JO - Dental Materials Journal
JF - Dental Materials Journal
SN - 0287-4547
IS - 4
ER -