Involvement of sulfatide in activation of protein kinase C by tumor promoters

Hirota Fujiki, Katsumi Yamashita, Masami Suganuma, Takahiko Horiuchi, Naoyuki Taniguchi, Akira Makita

研究成果: ジャーナルへの寄稿学術誌査読

7 被引用数 (Scopus)

抄録

Sulfatide (cerebroside sulfate) activated protein kinase C to the same extent as phosphatidylserine did with the tumor promoters, 12-0-tetradecanoylphorbol-13-acetate (TPA), teleocidin and debromo-aplysiatoxin. Sulfatide and phosphatidylserine both induced specific binding of [3H]TPA to protein kinase C, although the ratios of specific to non-specific [3H]TPA binding to protein kinase C with the two were not the same. It is concluded that sulfatide is involved in activation of protein kinase C by tumor promoters in a slightly different way from phosphatidylserine.

本文言語英語
ページ(範囲)153-158
ページ数6
ジャーナルBiochemical and Biophysical Research Communications
138
1
DOI
出版ステータス出版済み - 7月 16 1986
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 生物理学
  • 生化学
  • 分子生物学
  • 細胞生物学

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