Iridium-PPh 3 Catalysts for Conversion of Amides to Enamines

Yuta Une, Atsushi Tahara, Yasumitsu Miyamoto, Yusuke Sunada, Hideo Nagashima

研究成果: Contribution to journalArticle査読

10 被引用数 (Scopus)

抄録

Studies on the deactivation mechanism of the reaction of N,N-dialkylamides with TMDS catalyzed by Vaska's complex, IrCl(CO)(PPh 3 ) 2 (1a), triggered the discovery of highly active Ir-PPh 3 catalysts: Photochemically activated 1a and thermally activated IrCl(PPh 3 ) 3 (8). Both catalysts showed excellent activity toward the selective conversion of a variety of N,N-dialkyl-, N-alkyl-N-aryl-, and N,N-diarylamides to the corresponding enamines with low catalyst loadings. The 14-electron species "ClIr(PPh 3 ) 2 ", which is stabilized by solvents or reactants in the actual catalytic reactions, could be involved in the catalysis, which produces "HIr(PPh 3 ) 2 " and "SiIr(PPh 3 ) 2 " (Si = Me 2 HSiOMe 2 Siâ') species in the catalytic cycle. An in situ generation method for the "ClIrL 2 " species was established by simply mixing [IrCl(Ε 4 -COD)] 2 with PPh 3 or other phosphorus ligands, which realized the facile large-scale syntheses of enamines.

本文言語英語
ページ(範囲)852-862
ページ数11
ジャーナルOrganometallics
38
4
DOI
出版ステータス出版済み - 2 25 2019

All Science Journal Classification (ASJC) codes

  • 物理化学および理論化学
  • 有機化学
  • 無機化学

フィンガープリント

「Iridium-PPh <sub>3</sub> Catalysts for Conversion of Amides to Enamines」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル