Irreversible electroporation: Medical application of intense electric pulses for sustainable health

研究成果: 著書/レポートタイプへの貢献会議での発言

抄録

Irreversible electroporation (IRE) is a promising method for the ablation of tumors using intense electric pulses. Because the mechanism of IRE is based on the breaking of the cytoplasmic membrane, only the cells are necrotized non-Thermally without causing damage to the extracellular matrix when pulse settings are optimized to avoid Joule heating. In IRE therapy, a train of electric pulses of a few kilovolts is applied to the targeted tissue via a pair of electrodes. To definitely ablate the tissue and minimize the temperature rise during the application of pulses, determination of the adequate settings of the pulsesand electrode configuration prior to the therapy are important. Studies from the engineering perspective are therefore highly helpful for the successful use of IRE. In the current study, the authors' work associated with IRE will be introduced, including a 3D numerical simulation for the estimation of the electric field and temperature distribution around the electrodes, IRE experiment with a 3D cell culture model, and evaluation of cell destruction and thermal injury.

元の言語英語
ホスト出版物のタイトルSustainable Energy and Advanced Materials
ホスト出版物のサブタイトルProceeding of the 4th International Conference and Exhibition on Sustainable Energy and Advanced Materials 2015, ICE-SEAM 2015
出版者American Institute of Physics Inc.
1717
ISBN(電子版)9780735413658
DOI
出版物ステータス出版済み - 3 29 2016
イベント4th International Conference and Exhibition on Sustainable Energy and Advanced Materials 2015, ICE-SEAM 2015 - Solo, インドネシア
継続期間: 11 11 201511 12 2015

その他

その他4th International Conference and Exhibition on Sustainable Energy and Advanced Materials 2015, ICE-SEAM 2015
インドネシア
Solo
期間11/11/1511/12/15

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electric pulses
health
electrodes
therapy
Joule heating
pulses
cells
ablation
destruction
temperature distribution
tumors
engineering
membranes
damage
electric fields
evaluation
matrices
configurations
simulation
temperature

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)

これを引用

Kurata, K., & Takamatsu, H. (2016). Irreversible electroporation: Medical application of intense electric pulses for sustainable health. : Sustainable Energy and Advanced Materials: Proceeding of the 4th International Conference and Exhibition on Sustainable Energy and Advanced Materials 2015, ICE-SEAM 2015 (巻 1717). [4943424] American Institute of Physics Inc.. https://doi.org/10.1063/1.4943424

Irreversible electroporation : Medical application of intense electric pulses for sustainable health. / Kurata, Kosaku; Takamatsu, Hiroshi.

Sustainable Energy and Advanced Materials: Proceeding of the 4th International Conference and Exhibition on Sustainable Energy and Advanced Materials 2015, ICE-SEAM 2015. 巻 1717 American Institute of Physics Inc., 2016. 4943424.

研究成果: 著書/レポートタイプへの貢献会議での発言

Kurata, K & Takamatsu, H 2016, Irreversible electroporation: Medical application of intense electric pulses for sustainable health. : Sustainable Energy and Advanced Materials: Proceeding of the 4th International Conference and Exhibition on Sustainable Energy and Advanced Materials 2015, ICE-SEAM 2015. 巻. 1717, 4943424, American Institute of Physics Inc., 4th International Conference and Exhibition on Sustainable Energy and Advanced Materials 2015, ICE-SEAM 2015, Solo, インドネシア, 11/11/15. https://doi.org/10.1063/1.4943424
Kurata K, Takamatsu H. Irreversible electroporation: Medical application of intense electric pulses for sustainable health. : Sustainable Energy and Advanced Materials: Proceeding of the 4th International Conference and Exhibition on Sustainable Energy and Advanced Materials 2015, ICE-SEAM 2015. 巻 1717. American Institute of Physics Inc. 2016. 4943424 https://doi.org/10.1063/1.4943424
Kurata, Kosaku ; Takamatsu, Hiroshi. / Irreversible electroporation : Medical application of intense electric pulses for sustainable health. Sustainable Energy and Advanced Materials: Proceeding of the 4th International Conference and Exhibition on Sustainable Energy and Advanced Materials 2015, ICE-SEAM 2015. 巻 1717 American Institute of Physics Inc., 2016.
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