Isolation and structure of biologically active glycosphingolipids from the sea cucumber Cucumaria echinata

Koji Yamada, Eiji Hara, Tomofumi Miyamoto, Ryuichi Higuchi, Ryuichi Isobe, Seiichiroh Honda

研究成果: Contribution to journalArticle査読

45 被引用数 (Scopus)

抄録

Five cerebrosides, CE-1-1, CE-1-2, CE-1-3, CE-3-1, and CE-3-2, and a ganglioside molecular species CG-1 have been obtained from the less polar and polar fractions, respectively, of the chloroform/methanol extract of the sea cucumber Cucumaria echinata. The structures of these glycosphingohpids have been determined on the basis of chemical and spectroscopic evidence. The cerebrosides show lethality toward brine shrimps. On the other hand, the ganghoside CG-1 exhibits neuritogenic activity toward the rat pheochromocytoma cell line, PC-12 cells.

本文言語英語
ページ(範囲)371-378
ページ数8
ジャーナルEuropean Journal of Organic Chemistry
2
DOI
出版ステータス出版済み - 2 1998

All Science Journal Classification (ASJC) codes

  • 物理化学および理論化学
  • 有機化学

フィンガープリント

「Isolation and structure of biologically active glycosphingolipids from the sea cucumber Cucumaria echinata」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル