Isolation of new secondary metabolites from gorgonian soft coral Heteroxenia fuscescens collected from Red Sea

Fahd M. Abdelkarem, Ezz Eldin K. Desoky, Alaa M. Nafady, Ahmed E. Allam, Aldoushy Mahdy, Maki Nagata, Tomofumi Miyamoto, Kuniyoshi Shimizu

研究成果: Contribution to journalArticle査読

5 被引用数 (Scopus)

抄録

Further chemical study of the crude extract of the soft coral Heteroxenia fuscescens (Fam., Xeniidea), led to isolation of two new sterols, Heterofuscesterols A (1) and B (2), a sterol isolated for the first time from natural sources, 3β,5α,6β-trihydroxyandrosta-17-one (3), along with one new hydroperoxy sesquiterpene, Heterofusceterpene A (4), and one known ceramide (5). Their structures were elucidated by comprehensive spectroscopic analyses, including NMR and HRESIMS, and by comparison with previous data for related compounds in the literature. The cytotoxic activities of the isolated compounds were assessed using MTT colorimetric assay against MCF-7 and OVK-18 cancer cell lines.

本文言語英語
ページ(範囲)156-161
ページ数6
ジャーナルPhytochemistry Letters
36
DOI
出版ステータス出版済み - 4 2020

All Science Journal Classification (ASJC) codes

  • バイオテクノロジー
  • 生化学
  • 農業および作物学
  • 植物科学

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