Joint frequencies of alleles determined by separate formulations for the mating and mutation systems

Hidenori Tachida

研究成果: Contribution to journalArticle査読

9 被引用数 (Scopus)

抄録

A method to calculate joint gene frequencies, which are the probabilities that two neutral genes taken at random from a population have certain allelic states, is developed taking into account the effects of the mating system and the mutation scheme. We assume that the mutation rates are constant in the population and that the mating system does not depend on allelic states. Under either - the condition that mutation rates are symmetric or that the mating unit is large and the mutation rate is small - the general formula is represented by two terms, one for the mating system and the other for the mutation scheme. The term for the mating system is expressed using the coancestry coefficient in the infinite allele model, and the term for the mutation scheme is a function of the eigenvalues and the eigenvectors of the mutation matrix. Several examples are presented as applications of the method, including homozygosity in a stepping-stone model with a symmetric mutation scheme.

本文言語英語
ページ(範囲)963-974
ページ数12
ジャーナルGenetics
111
4
出版ステータス出版済み - 1985
外部発表はい

All Science Journal Classification (ASJC) codes

  • 遺伝学
  • 遺伝学(臨床)

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