Kinetic effect of cationic comb-type copolymers on DNA hybridization

Atsushi Maruyama, Longliang Wu, Naohiko Shimada, Arihiro Kano

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

抄録

We have been interested in the soluble interpolyelectrolyte complexes (IPEC) between DNA and the cationic comb-type copolymers, poly(L-lysine)-graft- dextran (PLL-g-Dex), consisting of a polylysine backbone and abundant hydrophilic graft chains of dextran as a model of nucleic acid-binding proteins. In this paper, we described the kinetic effect of the copolymers on the DNA hybridization. We found that the cationic copolymer at nano molar concentrations in cationic groups accelerated DNA duplex formation by two orders under physiologically relevant conditions.

本文言語英語
ホスト出版物のタイトルMulti-functional Materials and Structures - International Conference on Multifunctional Materials and Structures
出版社Trans Tech Publications
ページ1355-1358
ページ数4
ISBN(印刷版)0878493786, 9780878493784
DOI
出版ステータス出版済み - 2008
イベントMulti-functional Materials and Structures - International Conference on Multifunctional Materials and Structures - Hong Kong, P.R., 中国
継続期間: 7 28 20087 31 2008

出版物シリーズ

名前Advanced Materials Research
47-50 PART 2
ISSN(印刷版)1022-6680

その他

その他Multi-functional Materials and Structures - International Conference on Multifunctional Materials and Structures
Country中国
CityHong Kong, P.R.
Period7/28/087/31/08

All Science Journal Classification (ASJC) codes

  • Engineering(all)

フィンガープリント 「Kinetic effect of cationic comb-type copolymers on DNA hybridization」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル