@article{1452bb6a97a24413835af10852f309bd,
title = "Kinetic Modeling of an Enzyme Membrane Reactor for the Selective Production of Oligosaccharides",
abstract = "An enzyme membrane reactor is an attractive tool for producing oligosaccharides from biomass-based polysaccharides. However, kinetic modeling and reactor design based on the rate equations have rarely been reported for enzyme membrane reactors because of the difficulty in tracing the depolymerization process. In this study, a simplified reaction model based on Michaelis–Menten-type kinetics has been built to simulate the enzyme membrane reactor. Ramping various species into reactant, target, and byproduct worked well for discussing reactor performance. The use of a membrane with a molecular weight cut-off (MWCO) of 10 kDa with continuous feeding of the reactant was suggested for the efficient production of chitosan hexamer and pentamer by enzymatic hydrolysis of chitosan.",
author = "Shusaku Asano and Yosuke Muranaka and Taisuke Maki and Koki Ikeda and Kazuhiro Mae",
note = "Funding Information: S.A. acknowledges the support from the Cooperative Research Program of Network Joint Research Center for Materials and Devices that has been supported by the Ministry of Education, Culture, Sports, Science, and Technology (MEXT), Japan. All the authors acknowledge the support from Council for Science, Technology and Innovation (CSTI), Cross-ministerial Strategic Innovation Promotion Program (SIP), “Technologies for Smart Bioindustry and Agriculture” administered by Bio-oriented Technology Research Advancement Institution, and National Agriculture and Food Research Organization. Funding Information: This research was funded by JSPS KAKENHI (Grant number JP21H05083). Publisher Copyright: {\textcopyright} 2022 by the authors.",
year = "2022",
month = dec,
doi = "10.3390/fermentation8120701",
language = "English",
volume = "8",
journal = "Fermentation",
issn = "2311-5637",
publisher = "Multidisciplinary Digital Publishing Institute",
number = "12",
}