Hepatocellular carcinoma (HCC) with intrahepatic metastasis (IM) has a poor prognosis. In 1991 we carried out intra-hepatic-arterial LAK therapy for 3 HCC patients with IM. Case TY (45-year-old male) had a large tumor (diameter: 6 cm) in posterior segment with multiple intrahepatic metastases; Stage IV (T4N0M0) and underwent posterior segmentectomy (tw +: absolute non- curative operation). We carried out LAK therapy via the intra-hepatic-artery catheter. Therapeutic schedules consisted of LAK cells (1 x 109; twice/week), IL-2 (350 x 103JRU; 6 times/week) and cyclophosphamide (100 mg; once/week). We infused LAK cells 7 times in 5 weeks. Two years after LAK therapy, there were no IM stains in angiography and now, 6 and half years after this therapy, he is healthy without disease.
|出版ステータス||出版済み - 1月 1 1998|
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