Landmark-based reconstruction of 3D smooth structures from serial histological sections

Naoki Kawamura, Hirokazu Kobayashi, Tatsuya Yokota, Hidekata Hontani, Chika Iwamoto, Kenoki Ouchida, Makoto Hashizume

研究成果: 著書/レポートタイプへの貢献会議での発言

3 引用 (Scopus)

抄録

Given microscope images, one can observe 2D cross-sections of 3D micro anatomical structures with high spatial resolutions. Each of the 2D microscope images alone is, though, not suitable for studying the 3D anatomical structures and hence many works have been done on a 3D image reconstruction from a given series of microscope images of histological sections obtained from a single target tissue. For the 3D image reconstruction, an image registration technique is necessary because there exists the independent translation, rotation, and non-rigid deformation of the histological sections. In this paper, a landmark-based method of fully non-rigid image registration for the 3D image reconstruction is proposed. The proposed method first detects landmarks corresponded between given images by using a template matching and then non-rigidly deforms the images so that the corresponding landmarks detected in different images are located along a single smooth curve in the reconstructed 3D image. Most of all conventional methods for the reconstruction of 3D microscope image registers two consecutive images at a time and many micro anatomical structures often have unnatural straight shape along the vertical (z) direction in the resultant 3D image because, roughly speaking, the conventional methods registers two given images so that pixels with the same coordinates in the two images have the same pixel value. The proposed method, on the other hand, determine the deformations of all given images by referring to the all images and deforms them simultaneously. In the experiments, a 3D microscope image of the pancreas of a KPC mouse was reconstructed from a series of microscope images of the histological sections.

元の言語英語
ホスト出版物のタイトルMedical Imaging 2018
ホスト出版物のサブタイトルDigital Pathology
編集者Metin N. Gurcan, John E. Tomaszewski
出版者SPIE
ISBN(電子版)9781510616516
DOI
出版物ステータス出版済み - 1 1 2018
イベントMedical Imaging 2018: Digital Pathology - Houston, 米国
継続期間: 2 11 20182 12 2018

出版物シリーズ

名前Progress in Biomedical Optics and Imaging - Proceedings of SPIE
10581
ISSN(印刷物)1605-7422

その他

その他Medical Imaging 2018: Digital Pathology
米国
Houston
期間2/11/182/12/18

Fingerprint

landmarks
Microscopes
Computer-Assisted Image Processing
Image reconstruction
Image registration
Pixels
microscopes
Microstructure
Template matching
Pancreas
image reconstruction
registers
Tissue
pixels
pancreas
microstructure
Experiments

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

これを引用

Kawamura, N., Kobayashi, H., Yokota, T., Hontani, H., Iwamoto, C., Ouchida, K., & Hashizume, M. (2018). Landmark-based reconstruction of 3D smooth structures from serial histological sections. : M. N. Gurcan, & J. E. Tomaszewski (版), Medical Imaging 2018: Digital Pathology [105811E] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; 巻数 10581). SPIE. https://doi.org/10.1117/12.2293510

Landmark-based reconstruction of 3D smooth structures from serial histological sections. / Kawamura, Naoki; Kobayashi, Hirokazu; Yokota, Tatsuya; Hontani, Hidekata; Iwamoto, Chika; Ouchida, Kenoki; Hashizume, Makoto.

Medical Imaging 2018: Digital Pathology. 版 / Metin N. Gurcan; John E. Tomaszewski. SPIE, 2018. 105811E (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; 巻 10581).

研究成果: 著書/レポートタイプへの貢献会議での発言

Kawamura, N, Kobayashi, H, Yokota, T, Hontani, H, Iwamoto, C, Ouchida, K & Hashizume, M 2018, Landmark-based reconstruction of 3D smooth structures from serial histological sections. : MN Gurcan & JE Tomaszewski (版), Medical Imaging 2018: Digital Pathology., 105811E, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 巻. 10581, SPIE, Medical Imaging 2018: Digital Pathology, Houston, 米国, 2/11/18. https://doi.org/10.1117/12.2293510
Kawamura N, Kobayashi H, Yokota T, Hontani H, Iwamoto C, Ouchida K その他. Landmark-based reconstruction of 3D smooth structures from serial histological sections. : Gurcan MN, Tomaszewski JE, 編集者, Medical Imaging 2018: Digital Pathology. SPIE. 2018. 105811E. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). https://doi.org/10.1117/12.2293510
Kawamura, Naoki ; Kobayashi, Hirokazu ; Yokota, Tatsuya ; Hontani, Hidekata ; Iwamoto, Chika ; Ouchida, Kenoki ; Hashizume, Makoto. / Landmark-based reconstruction of 3D smooth structures from serial histological sections. Medical Imaging 2018: Digital Pathology. 編集者 / Metin N. Gurcan ; John E. Tomaszewski. SPIE, 2018. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).
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