抄録
Objective: The purpose of this study was to evaluate the hemodynamic changes in left ventricular function before and after patent ductus arteriosus ligation in premature infants with regard to the energetic efficiency of left ventricular pumping. Methods: Thirty-five premature infants who underwent patent ductus arteriosus ligation were enrolled in this study. Left ventricular efficiency was evaluated at 4 points: within 24 hours before patent ductus arteriosus ligation, within 24 hours after patent ductus arteriosus ligation, between postoperative days 2 and 4, and on postoperative day 7. The indices of contractility (end-systolic elastance) and afterload (effective arterial elastance) were approximated on the basis of the systemic blood pressure and systolic or diastolic left ventricular volume. The ratio of stroke work and pressure-volume area, representing the ventricular efficiency, was estimated using the following theoretic formula: the ratio of stroke work and pressure-volume area = 1/(1 + 0.5 ventriculoarterial coupling). Results: Left ventricular efficiency was transiently deteriorated within 24 hours after patent ductus arteriosus ligation because of the marked increase of the afterload and the slight increase of contraction, and then recovered to preoperation levels by 2 to 4 days after patent ductus arteriosus ligation. Conclusions: Analysis of indices representing the afterload, contractility, and energetic efficiency of the left ventricle may provide practical information for the management of premature infants during the postoperative period after patent ductus arteriosus ligation.
| 元の言語 | 英語 |
|---|---|
| ページ（範囲） | 1353-1358 |
| ページ数 | 6 |
| ジャーナル | Journal of Thoracic and Cardiovascular Surgery |
| 巻 | 146 |
| 発行部数 | 6 |
| DOI | |
| 出版物ステータス | 出版済み - 12 1 2013 |
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All Science Journal Classification (ASJC) codes
- Surgery
- Pulmonary and Respiratory Medicine
- Cardiology and Cardiovascular Medicine
これを引用
Left ventricular efficiency after ligation of patent ductus arteriosus for premature infants. / Nagata, Hazumu; Ihara, Kenji; Yamamura, Kenichiro; Tanoue, Yoshihisa; Shiokawa, Yuichi; Tominaga, Ryuji; Hara, Toshiro.
：: Journal of Thoracic and Cardiovascular Surgery, 巻 146, 番号 6, 01.12.2013, p. 1353-1358.研究成果: ジャーナルへの寄稿 › 記事
}
TY - JOUR
T1 - Left ventricular efficiency after ligation of patent ductus arteriosus for premature infants
AU - Nagata, Hazumu
AU - Ihara, Kenji
AU - Yamamura, Kenichiro
AU - Tanoue, Yoshihisa
AU - Shiokawa, Yuichi
AU - Tominaga, Ryuji
AU - Hara, Toshiro
PY - 2013/12/1
Y1 - 2013/12/1
N2 - Objective: The purpose of this study was to evaluate the hemodynamic changes in left ventricular function before and after patent ductus arteriosus ligation in premature infants with regard to the energetic efficiency of left ventricular pumping. Methods: Thirty-five premature infants who underwent patent ductus arteriosus ligation were enrolled in this study. Left ventricular efficiency was evaluated at 4 points: within 24 hours before patent ductus arteriosus ligation, within 24 hours after patent ductus arteriosus ligation, between postoperative days 2 and 4, and on postoperative day 7. The indices of contractility (end-systolic elastance) and afterload (effective arterial elastance) were approximated on the basis of the systemic blood pressure and systolic or diastolic left ventricular volume. The ratio of stroke work and pressure-volume area, representing the ventricular efficiency, was estimated using the following theoretic formula: the ratio of stroke work and pressure-volume area = 1/(1 + 0.5 ventriculoarterial coupling). Results: Left ventricular efficiency was transiently deteriorated within 24 hours after patent ductus arteriosus ligation because of the marked increase of the afterload and the slight increase of contraction, and then recovered to preoperation levels by 2 to 4 days after patent ductus arteriosus ligation. Conclusions: Analysis of indices representing the afterload, contractility, and energetic efficiency of the left ventricle may provide practical information for the management of premature infants during the postoperative period after patent ductus arteriosus ligation.
AB - Objective: The purpose of this study was to evaluate the hemodynamic changes in left ventricular function before and after patent ductus arteriosus ligation in premature infants with regard to the energetic efficiency of left ventricular pumping. Methods: Thirty-five premature infants who underwent patent ductus arteriosus ligation were enrolled in this study. Left ventricular efficiency was evaluated at 4 points: within 24 hours before patent ductus arteriosus ligation, within 24 hours after patent ductus arteriosus ligation, between postoperative days 2 and 4, and on postoperative day 7. The indices of contractility (end-systolic elastance) and afterload (effective arterial elastance) were approximated on the basis of the systemic blood pressure and systolic or diastolic left ventricular volume. The ratio of stroke work and pressure-volume area, representing the ventricular efficiency, was estimated using the following theoretic formula: the ratio of stroke work and pressure-volume area = 1/(1 + 0.5 ventriculoarterial coupling). Results: Left ventricular efficiency was transiently deteriorated within 24 hours after patent ductus arteriosus ligation because of the marked increase of the afterload and the slight increase of contraction, and then recovered to preoperation levels by 2 to 4 days after patent ductus arteriosus ligation. Conclusions: Analysis of indices representing the afterload, contractility, and energetic efficiency of the left ventricle may provide practical information for the management of premature infants during the postoperative period after patent ductus arteriosus ligation.
UR - http://www.scopus.com/inward/record.url?scp=84888068282&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84888068282&partnerID=8YFLogxK
U2 - 10.1016/j.jtcvs.2013.02.019
DO - 10.1016/j.jtcvs.2013.02.019
M3 - Article
C2 - 23473013
AN - SCOPUS:84888068282
VL - 146
SP - 1353
EP - 1358
JO - Journal of Thoracic and Cardiovascular Surgery
JF - Journal of Thoracic and Cardiovascular Surgery
SN - 0022-5223
IS - 6
ER -