Left ventricular performance after aortic valve replacement in patients with low ejection fraction

Yoshihisa Tanoue, Yasuhisa Oishi, Hiromichi Sonoda, Takahiro Nishida, Atsuhiro Nakashima, Ryuji Tominaga

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

抄録

The operative validity of aortic valve replacement (AVR) for high-risk patients with impaired left ventricular (LV) function is controversial. We measured LV contractility, afterload, and efficiency by use of transthoracic echocardiography data obtained before, after, and approximately 1 year after isolated AVR for 335 patients with aortic stenosis (AS group; n = 160), aortic regurgitation (AR group; n = 116), or aortic stenosis and regurgitation (ASR group; n = 59). Two subgroups were created: LV ejection fraction (EF) of ≥50 % (normal-EF subgroup) and <50 % (low-EF subgroup). Contractility decreased after AVR in the normal-EF AS and normal-EF AR subgroups, but did not change after AVR in the low-EF subgroups. Afterload decreased after AVR in the AS group and increased in the AR group. LV efficiency was unchanged after AVR in the normal-EF AS and ASR subgroups, worsened in the normal-EF AR subgroup, improved in the low-EF AS and ASR subgroups, and did not improve in the low-EF AR subgroup. LV contractility and efficiency improved during the 1-year period after AVR for all patients and subgroups, but the improvements in the low-EF AR subgroup were not as good as those in the low-EF AS and ASR subgroups. Improvements in LV contractility and efficiency after AVR can be expected for patients with low EF. However, contractility and efficiency did not improve after AVR for patients with AR and low EF. Low mortality and morbidity of AVR likely conceal a latent problem among patients with AR.

元の言語英語
ページ(範囲)443-450
ページ数8
ジャーナルJournal of Artificial Organs
16
発行部数4
DOI
出版物ステータス出版済み - 12 1 2013

Fingerprint

Aortic Valve
Echocardiography
Aortic Valve Insufficiency
Aortic Valve Stenosis
Left Ventricular Function
Stroke Volume
Morbidity
Mortality

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering
  • Cardiology and Cardiovascular Medicine

これを引用

Left ventricular performance after aortic valve replacement in patients with low ejection fraction. / Tanoue, Yoshihisa; Oishi, Yasuhisa; Sonoda, Hiromichi; Nishida, Takahiro; Nakashima, Atsuhiro; Tominaga, Ryuji.

:: Journal of Artificial Organs, 巻 16, 番号 4, 01.12.2013, p. 443-450.

研究成果: ジャーナルへの寄稿記事

@article{96ea670c2ac1474fb29bac52ae31675d,
title = "Left ventricular performance after aortic valve replacement in patients with low ejection fraction",
abstract = "The operative validity of aortic valve replacement (AVR) for high-risk patients with impaired left ventricular (LV) function is controversial. We measured LV contractility, afterload, and efficiency by use of transthoracic echocardiography data obtained before, after, and approximately 1 year after isolated AVR for 335 patients with aortic stenosis (AS group; n = 160), aortic regurgitation (AR group; n = 116), or aortic stenosis and regurgitation (ASR group; n = 59). Two subgroups were created: LV ejection fraction (EF) of ≥50 {\%} (normal-EF subgroup) and <50 {\%} (low-EF subgroup). Contractility decreased after AVR in the normal-EF AS and normal-EF AR subgroups, but did not change after AVR in the low-EF subgroups. Afterload decreased after AVR in the AS group and increased in the AR group. LV efficiency was unchanged after AVR in the normal-EF AS and ASR subgroups, worsened in the normal-EF AR subgroup, improved in the low-EF AS and ASR subgroups, and did not improve in the low-EF AR subgroup. LV contractility and efficiency improved during the 1-year period after AVR for all patients and subgroups, but the improvements in the low-EF AR subgroup were not as good as those in the low-EF AS and ASR subgroups. Improvements in LV contractility and efficiency after AVR can be expected for patients with low EF. However, contractility and efficiency did not improve after AVR for patients with AR and low EF. Low mortality and morbidity of AVR likely conceal a latent problem among patients with AR.",
author = "Yoshihisa Tanoue and Yasuhisa Oishi and Hiromichi Sonoda and Takahiro Nishida and Atsuhiro Nakashima and Ryuji Tominaga",
year = "2013",
month = "12",
day = "1",
doi = "10.1007/s10047-013-0730-4",
language = "English",
volume = "16",
pages = "443--450",
journal = "Journal of Artificial Organs",
issn = "1434-7229",
publisher = "Springer Japan",
number = "4",

}

TY - JOUR

T1 - Left ventricular performance after aortic valve replacement in patients with low ejection fraction

AU - Tanoue, Yoshihisa

AU - Oishi, Yasuhisa

AU - Sonoda, Hiromichi

AU - Nishida, Takahiro

AU - Nakashima, Atsuhiro

AU - Tominaga, Ryuji

PY - 2013/12/1

Y1 - 2013/12/1

N2 - The operative validity of aortic valve replacement (AVR) for high-risk patients with impaired left ventricular (LV) function is controversial. We measured LV contractility, afterload, and efficiency by use of transthoracic echocardiography data obtained before, after, and approximately 1 year after isolated AVR for 335 patients with aortic stenosis (AS group; n = 160), aortic regurgitation (AR group; n = 116), or aortic stenosis and regurgitation (ASR group; n = 59). Two subgroups were created: LV ejection fraction (EF) of ≥50 % (normal-EF subgroup) and <50 % (low-EF subgroup). Contractility decreased after AVR in the normal-EF AS and normal-EF AR subgroups, but did not change after AVR in the low-EF subgroups. Afterload decreased after AVR in the AS group and increased in the AR group. LV efficiency was unchanged after AVR in the normal-EF AS and ASR subgroups, worsened in the normal-EF AR subgroup, improved in the low-EF AS and ASR subgroups, and did not improve in the low-EF AR subgroup. LV contractility and efficiency improved during the 1-year period after AVR for all patients and subgroups, but the improvements in the low-EF AR subgroup were not as good as those in the low-EF AS and ASR subgroups. Improvements in LV contractility and efficiency after AVR can be expected for patients with low EF. However, contractility and efficiency did not improve after AVR for patients with AR and low EF. Low mortality and morbidity of AVR likely conceal a latent problem among patients with AR.

AB - The operative validity of aortic valve replacement (AVR) for high-risk patients with impaired left ventricular (LV) function is controversial. We measured LV contractility, afterload, and efficiency by use of transthoracic echocardiography data obtained before, after, and approximately 1 year after isolated AVR for 335 patients with aortic stenosis (AS group; n = 160), aortic regurgitation (AR group; n = 116), or aortic stenosis and regurgitation (ASR group; n = 59). Two subgroups were created: LV ejection fraction (EF) of ≥50 % (normal-EF subgroup) and <50 % (low-EF subgroup). Contractility decreased after AVR in the normal-EF AS and normal-EF AR subgroups, but did not change after AVR in the low-EF subgroups. Afterload decreased after AVR in the AS group and increased in the AR group. LV efficiency was unchanged after AVR in the normal-EF AS and ASR subgroups, worsened in the normal-EF AR subgroup, improved in the low-EF AS and ASR subgroups, and did not improve in the low-EF AR subgroup. LV contractility and efficiency improved during the 1-year period after AVR for all patients and subgroups, but the improvements in the low-EF AR subgroup were not as good as those in the low-EF AS and ASR subgroups. Improvements in LV contractility and efficiency after AVR can be expected for patients with low EF. However, contractility and efficiency did not improve after AVR for patients with AR and low EF. Low mortality and morbidity of AVR likely conceal a latent problem among patients with AR.

UR - http://www.scopus.com/inward/record.url?scp=84891494265&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84891494265&partnerID=8YFLogxK

U2 - 10.1007/s10047-013-0730-4

DO - 10.1007/s10047-013-0730-4

M3 - Article

C2 - 24036623

AN - SCOPUS:84891494265

VL - 16

SP - 443

EP - 450

JO - Journal of Artificial Organs

JF - Journal of Artificial Organs

SN - 1434-7229

IS - 4

ER -