Lesch-Nyhan syndrome (LNS) is a disorder caused by congenital absence of a purine metabolic enzyme, hypoxanthine guanine phosphoribosyltransferase (HGPRT). This syndrome is characterized clinically by hyperuricemia and neurologic features including choreoathetoid spasticity, self-mutilation, and mental retardation. We report on a patient in whom self-mutilation of the lower lip was suppressed with the help of a mouth guard made from soft resin.
|ジャーナル||International Journal of Oral and Maxillofacial Surgery|
|出版ステータス||出版済み - 2 1994|
All Science Journal Classification (ASJC) codes
- Oral Surgery