Lipopolysaccharide-Induced Monocytic Cell Death for the Diagnosis of Mild Neonatal-Onset Multisystem Inflammatory Disease

Hidetoshi Takada, Masataka Ishimura, Hiroko Inada, Shouichi Ohga, Koichi Kusuhara, Yoichi Moroi, Masutaka Furue, Toshiro Hara

研究成果: Contribution to journalArticle査読

4 被引用数 (Scopus)

抄録

In this report, we describe a boy who showed mild symptoms of neonatal-onset multisystem inflammatory disease. Although his symptoms and laboratory findings were similar to those of systemic juvenile idiopathic arthritis, further examinations revealed papilledema, meningitis, and a NLRP3 mutation. His peripheral blood monocytes died within 24 hours after lipopolysaccharide stimulation, a test that may be useful for diagnosis even in mild cases.

本文言語英語
ページ(範囲)885-887.e1
ジャーナルJournal of Pediatrics
152
6
DOI
出版ステータス出版済み - 6 2008

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

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