肝門部領域胆管癌術後の難治性細胆管炎に起因すると思われる肝不全に対し 抗菌薬動注療法が奏効した1 例

Masataka Hayashi, Yasuhisa Mori, Ohtsuka Takao, Kohei Nakata, Yoshihiro Miyasaka, Yoshiki Asayama, Kazuhiro Koto, Masafumi Nakamura

研究成果: ジャーナルへの寄稿記事

抄録

We present a 65-year-old man who underwent left hepatic trisegmentectomy and biliary reconstruction for hilar cholangiocarcinoma. Four months after the operation, serum total bilirubin level was elevated to 24.1 mg/dl. CT revealed a migrated biliary stent in the intrahepatic bile duct. The stent was successfully removed under percutaneous transhepatic approach; however, serum total bilirubin level did not decreased. The diagnosis of liver failure caused by refractory cholangitis was made and, intra-arterial antibiotic therapy using meropenem and ciprofloxacin was performed, and thereafter, the serum total bilirubin promptly decreased. This case report suggests that intra-arterial antibiotic therapy seems to be effective for liver failure caused by refractory cholangitis after major hepatectomy with biliary reconstruction.

元の言語Japanese
ページ(範囲)45-52
ページ数8
ジャーナルJapanese Journal of Gastroenterological Surgery
52
発行部数1
DOI
出版物ステータス出版済み - 1 1 2019

Fingerprint

Klatskin Tumor
Cholangitis
Liver Failure
Bilirubin
meropenem
Anti-Bacterial Agents
Stents
Serum
Intrahepatic Bile Ducts
Hepatectomy
Ciprofloxacin
Therapeutics
Liver

All Science Journal Classification (ASJC) codes

  • Surgery
  • Gastroenterology

これを引用

@article{49dacad651df4cad833c9acc604b3e92,
title = "肝門部領域胆管癌術後の難治性細胆管炎に起因すると思われる肝不全に対し 抗菌薬動注療法が奏効した1 例",
abstract = "We present a 65-year-old man who underwent left hepatic trisegmentectomy and biliary reconstruction for hilar cholangiocarcinoma. Four months after the operation, serum total bilirubin level was elevated to 24.1 mg/dl. CT revealed a migrated biliary stent in the intrahepatic bile duct. The stent was successfully removed under percutaneous transhepatic approach; however, serum total bilirubin level did not decreased. The diagnosis of liver failure caused by refractory cholangitis was made and, intra-arterial antibiotic therapy using meropenem and ciprofloxacin was performed, and thereafter, the serum total bilirubin promptly decreased. This case report suggests that intra-arterial antibiotic therapy seems to be effective for liver failure caused by refractory cholangitis after major hepatectomy with biliary reconstruction.",
author = "Masataka Hayashi and Yasuhisa Mori and Ohtsuka Takao and Kohei Nakata and Yoshihiro Miyasaka and Yoshiki Asayama and Kazuhiro Koto and Masafumi Nakamura",
year = "2019",
month = "1",
day = "1",
doi = "10.5833/jjgs.2017.0116",
language = "Japanese",
volume = "52",
pages = "45--52",
journal = "Japanese Journal of Gastroenterological Surgery",
issn = "0386-9768",
publisher = "Japanese Society of Gastroenterological Surgery",
number = "1",

}

TY - JOUR

T1 - 肝門部領域胆管癌術後の難治性細胆管炎に起因すると思われる肝不全に対し 抗菌薬動注療法が奏効した1 例

AU - Hayashi, Masataka

AU - Mori, Yasuhisa

AU - Takao, Ohtsuka

AU - Nakata, Kohei

AU - Miyasaka, Yoshihiro

AU - Asayama, Yoshiki

AU - Koto, Kazuhiro

AU - Nakamura, Masafumi

PY - 2019/1/1

Y1 - 2019/1/1

N2 - We present a 65-year-old man who underwent left hepatic trisegmentectomy and biliary reconstruction for hilar cholangiocarcinoma. Four months after the operation, serum total bilirubin level was elevated to 24.1 mg/dl. CT revealed a migrated biliary stent in the intrahepatic bile duct. The stent was successfully removed under percutaneous transhepatic approach; however, serum total bilirubin level did not decreased. The diagnosis of liver failure caused by refractory cholangitis was made and, intra-arterial antibiotic therapy using meropenem and ciprofloxacin was performed, and thereafter, the serum total bilirubin promptly decreased. This case report suggests that intra-arterial antibiotic therapy seems to be effective for liver failure caused by refractory cholangitis after major hepatectomy with biliary reconstruction.

AB - We present a 65-year-old man who underwent left hepatic trisegmentectomy and biliary reconstruction for hilar cholangiocarcinoma. Four months after the operation, serum total bilirubin level was elevated to 24.1 mg/dl. CT revealed a migrated biliary stent in the intrahepatic bile duct. The stent was successfully removed under percutaneous transhepatic approach; however, serum total bilirubin level did not decreased. The diagnosis of liver failure caused by refractory cholangitis was made and, intra-arterial antibiotic therapy using meropenem and ciprofloxacin was performed, and thereafter, the serum total bilirubin promptly decreased. This case report suggests that intra-arterial antibiotic therapy seems to be effective for liver failure caused by refractory cholangitis after major hepatectomy with biliary reconstruction.

UR - http://www.scopus.com/inward/record.url?scp=85061731114&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85061731114&partnerID=8YFLogxK

U2 - 10.5833/jjgs.2017.0116

DO - 10.5833/jjgs.2017.0116

M3 - 記事

VL - 52

SP - 45

EP - 52

JO - Japanese Journal of Gastroenterological Surgery

JF - Japanese Journal of Gastroenterological Surgery

SN - 0386-9768

IS - 1

ER -