Localization and abundance of early markers of fat cell differentiation in the skeletal muscle of cattle during growth - Are DLK1-positive cells the origin of marbling flecks?

Elke Albrecht, Judith Kuzinski, Katrin Komolka, Takafumi Gotoh, Steffen Maak

研究成果: Contribution to journalArticle査読

10 被引用数 (Scopus)

抄録

Localization and abundance of early markers of adipogenic differentiation were investigated in bovine muscle tissue to verify their association with marbling development. Bovine skeletal muscle samples were used for immunohistochemical localization and measurement of mRNA and protein abundance of delta-like homolog 1 (DLK1) and CCAAT/enhancer-binding protein beta (CEBPB). The localization of DLK1-positive cells confirmed the position of small clusters of adipocytes which can be considered as the origin of marbling flecks. The results indicated higher DLK1 expression in the less marbled muscle of Holstein (HS) steers (. P<. 0.05) and a trend to higher CEBPB expression in Japanese Black (JB) steers (. P<. 0.1) at slaughter. The number of DLK1-positive cells and fat content were negatively correlated. The lower expression of DLK1 together with higher CEBPB abundance during fattening in JB may have contributed to the development of more adipocytes in the skeletal muscle of JB.

本文言語英語
ページ(範囲)237-245
ページ数9
ジャーナルMeat Science
100
DOI
出版ステータス出版済み - 2 1 2015

All Science Journal Classification (ASJC) codes

  • 食品科学

フィンガープリント

「Localization and abundance of early markers of fat cell differentiation in the skeletal muscle of cattle during growth - Are DLK1-positive cells the origin of marbling flecks?」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル