Loneliness inside of the brain: evidence from a large dataset of resting-state fMRI in young adult

Denilson Brilliant T, Hikaru Takeuchi, Rui Nouchi, Ryoichi Yokoyama, Yuka Kotozaki, Seishu Nakagawa, Sugiko Hanawa, Atsushi Sekiguchi, Shigeyuki Ikeda, Kohei Sakaki, Kelssy Hitomi dos Santos Kawata, Takayuki Nozawa, Susumu Yokota, Daniele Magistro, Ryuta Kawashima

研究成果: ジャーナルへの寄稿学術誌査読

1 被引用数 (Scopus)

抄録

Although loneliness itself is a natural emotion, prolonged loneliness is detrimental to human health. Despite its detrimental effect, few loneliness-related neuroimaging studies have been published and some have limitations on the sample size number. This study aims to find the difference in resting-state functional connectivity associated with loneliness within a big sample size via the seed-based approach. Functional connectivity analysis was performed on a large cohort of young adults (N = 1336) using the seed-based functional connectivity approach to address the concern from previous studies. The analysis yielded statistically significant positive correlations between loneliness and functional connectivities between the inferior frontal gyrus and supplementary motor area, precentral gyrus, and superior parietal lobule. Additionally, the analysis replicated a finding from a previous study, which is increased functional connectivities between the inferior frontal gyrus and supplementary motor area. In conclusion, greater loneliness is reflected by stronger functional connectivity of the visual attention brain area.

本文言語英語
論文番号7856
ジャーナルScientific reports
12
1
DOI
出版ステータス出版済み - 12月 2022

!!!All Science Journal Classification (ASJC) codes

  • 一般

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