Long-term hearing outcome after retrosigmoid removal of vestibular schwannoma

Akira Nakamizo, Megumu Mori, Daisuke Inoue, Toshiyuki Amano, Masahiro Mizoguchi, Koji Yoshimoto, Tomio Sasaki

研究成果: Contribution to journalArticle

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Although many investigators have reported the hearing function in the immediate postoperative period in patients with vestibular schwannoma (VS), little is known about the long-term outcomes of the postoperative hearing. The aim of this study was to analyze the long-term hearing outcomes at a mean followup of 5 years in patients with unilateral VS treated via the retrosigmoid approach. Twenty-four patients with immediate postoperative serviceable hearing who underwent repeated audiogram or phone interview were included in this study. During the mean follow-up period (68.8 ± 30.2 months, range 14-123 months), serviceable hearing was preserved in 20 out of the 24 patients (83%). Pure tone average (PTA) was reevaluated within 6 months in seven patients. In the two patients whose PTA deteriorated ≥ 5 dB in 6 months after surgery, their PTA worsened ≥ 15 dB compared to the immediate postoperative PTA. In the remaining five patients whose PTA deteriorated < 5 dB in 6 months after surgery, PTA was maintained within a 15-dB deterioration at the final follow-up (p = 0.04, Fisher's exact test). According to Kaplan- Meier survival plots, the 5-year or 7-year preservation rate of serviceable hearing was 86.2% or 71.8%, respectively. Further study will be needed to clarify the mechanism underlying the long-term decline of serviceable hearing; however, the deterioration of PTA in the early postoperative period may help to predict the long-term outcomes of hearing.

元の言語英語
ページ(範囲)688-694
ページ数7
ジャーナルNeurologia medico-chirurgica
53
発行部数10
DOI
出版物ステータス出版済み - 2013

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

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