Long-term regular exercise and intraocular pressure: the Hisayama Study

Kohta Fujiwara, Miho Yasuda, Jun Hata, Daigo Yoshida, Hiro Kishimoto, Sawako Hashimoto, Takeshi Yoshitomi, Toshiharu Ninomiya, Koh Hei Sonoda

研究成果: ジャーナルへの寄稿記事

抄録

Purpose: To investigate the association between long-term regular exercise (exercise frequency and exercise time) and 5-year changes in intraocular pressure in a general Japanese population. Methods: This population-based, cohort study was conducted in 2007. A total of 3119 Japanese community dwellers aged ≥ 40 years underwent eye examinations including intraocular pressure measurement with a noncontact tonometer. Of these, 1871 subjects (801 men and 1070 women) who underwent intraocular pressure measurement in 2012 participated. We assessed the associations of exercise frequency and exercise time with intraocular pressure using a linear regression model, adjusted for age and possible risk factors that can affect intraocular pressure. Results: The mean 5-year intraocular pressure change ± standard deviation was − 0.84 ± 1.9 mmHg. After adjustment for age, sex, systolic blood pressure, diabetes, total cholesterol, high-density lipoprotein cholesterol, body mass index, waist circumference, smoking habit, alcohol intake, work intensity levels, and intraocular pressure at baseline, we observed that increased exercise frequency (times/week) and increased exercise time (min/week) were both significantly associated with reduced intraocular pressure (p < 0.05 each). In the subgroup analyses based on the presence/absence of possible confounding risk factors, there was no evidence of heterogeneity among all subgroups (p for heterogeneity > 0.2). Conclusions: Increased exercise frequency levels and increased exercise time are both independently associated with reduced intraocular pressure levels after adjustment for confounding factors.

元の言語英語
ページ(範囲)2461-2469
ページ数9
ジャーナルGraefe's Archive for Clinical and Experimental Ophthalmology
257
発行部数11
DOI
出版物ステータス出版済み - 11 1 2019

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Intraocular Pressure
Exercise
Linear Models
Blood Pressure
Waist Circumference
HDL Cholesterol
Population
Habits
Body Mass Index
Cohort Studies
Smoking
Cholesterol
Alcohols

All Science Journal Classification (ASJC) codes

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

これを引用

Long-term regular exercise and intraocular pressure : the Hisayama Study. / Fujiwara, Kohta; Yasuda, Miho; Hata, Jun; Yoshida, Daigo; Kishimoto, Hiro; Hashimoto, Sawako; Yoshitomi, Takeshi; Ninomiya, Toshiharu; Sonoda, Koh Hei.

:: Graefe's Archive for Clinical and Experimental Ophthalmology, 巻 257, 番号 11, 01.11.2019, p. 2461-2469.

研究成果: ジャーナルへの寄稿記事

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abstract = "Purpose: To investigate the association between long-term regular exercise (exercise frequency and exercise time) and 5-year changes in intraocular pressure in a general Japanese population. Methods: This population-based, cohort study was conducted in 2007. A total of 3119 Japanese community dwellers aged ≥ 40 years underwent eye examinations including intraocular pressure measurement with a noncontact tonometer. Of these, 1871 subjects (801 men and 1070 women) who underwent intraocular pressure measurement in 2012 participated. We assessed the associations of exercise frequency and exercise time with intraocular pressure using a linear regression model, adjusted for age and possible risk factors that can affect intraocular pressure. Results: The mean 5-year intraocular pressure change ± standard deviation was − 0.84 ± 1.9 mmHg. After adjustment for age, sex, systolic blood pressure, diabetes, total cholesterol, high-density lipoprotein cholesterol, body mass index, waist circumference, smoking habit, alcohol intake, work intensity levels, and intraocular pressure at baseline, we observed that increased exercise frequency (times/week) and increased exercise time (min/week) were both significantly associated with reduced intraocular pressure (p < 0.05 each). In the subgroup analyses based on the presence/absence of possible confounding risk factors, there was no evidence of heterogeneity among all subgroups (p for heterogeneity > 0.2). Conclusions: Increased exercise frequency levels and increased exercise time are both independently associated with reduced intraocular pressure levels after adjustment for confounding factors.",
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AU - Fujiwara, Kohta

AU - Yasuda, Miho

AU - Hata, Jun

AU - Yoshida, Daigo

AU - Kishimoto, Hiro

AU - Hashimoto, Sawako

AU - Yoshitomi, Takeshi

AU - Ninomiya, Toshiharu

AU - Sonoda, Koh Hei

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