Longitudinally extensive myelopathy in Caucasians: A West Australian study of 26 cases from the Perth Demyelinating Diseases Database

W. Qiu, J. S. Wu, M. N. Zhang, Takuya Matsushita, Jun-Ichi Kira, W. M. Carroll, F. L. Mastaglia, A. G. Kermode

研究成果: ジャーナルへの寄稿記事

27 引用 (Scopus)

抄録

Objectives: To characterise West Australian cases of longitudinally extensive myelopathy (LEM). Methods: Twenty six patients with LEM were identified from a cohort of 983 patients with demyelinating disease. Clinical and MRI data and AQP4-IgG results were reviewed. Results: LEM cases were classified as conventional MS (CMS) 13, neuromyelitis optica (NMO) 7, and isolated LEM 6. LEM was the initial presentation in 13/26 cases. In CMS cases lesions were mainly in the lower cervical cord (C4-C7) whereas in NMO and isolated LEM they were more often thoracic and were longer. The severity of disability was highly variable but was greater in the NMO than the CMS group. Only one of 20 patients tested was seropositive for AQP4-IgG. Conclusion LEM occurred as part of CMS or NMO or in isolation. Patients with LEM had highly heterogeneous clinical characteristics and a low rate of AQP4-IgG seropositivity.

元の言語英語
ページ(範囲)209-212
ページ数4
ジャーナルJournal of Neurology, Neurosurgery and Psychiatry
81
発行部数2
DOI
出版物ステータス出版済み - 1 1 2010

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Spinal Cord Diseases
Demyelinating Diseases
Databases
Neuromyelitis Optica
Immunoglobulin G
Thorax

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology
  • Psychiatry and Mental health

これを引用

Longitudinally extensive myelopathy in Caucasians : A West Australian study of 26 cases from the Perth Demyelinating Diseases Database. / Qiu, W.; Wu, J. S.; Zhang, M. N.; Matsushita, Takuya; Kira, Jun-Ichi; Carroll, W. M.; Mastaglia, F. L.; Kermode, A. G.

:: Journal of Neurology, Neurosurgery and Psychiatry, 巻 81, 番号 2, 01.01.2010, p. 209-212.

研究成果: ジャーナルへの寄稿記事

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abstract = "Objectives: To characterise West Australian cases of longitudinally extensive myelopathy (LEM). Methods: Twenty six patients with LEM were identified from a cohort of 983 patients with demyelinating disease. Clinical and MRI data and AQP4-IgG results were reviewed. Results: LEM cases were classified as conventional MS (CMS) 13, neuromyelitis optica (NMO) 7, and isolated LEM 6. LEM was the initial presentation in 13/26 cases. In CMS cases lesions were mainly in the lower cervical cord (C4-C7) whereas in NMO and isolated LEM they were more often thoracic and were longer. The severity of disability was highly variable but was greater in the NMO than the CMS group. Only one of 20 patients tested was seropositive for AQP4-IgG. Conclusion LEM occurred as part of CMS or NMO or in isolation. Patients with LEM had highly heterogeneous clinical characteristics and a low rate of AQP4-IgG seropositivity.",
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AU - Wu, J. S.

AU - Zhang, M. N.

AU - Matsushita, Takuya

AU - Kira, Jun-Ichi

AU - Carroll, W. M.

AU - Mastaglia, F. L.

AU - Kermode, A. G.

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