Magnetic immunoassays utilizing magnetic markers and a high-TC SQUID

K. Enpuku, K. Inoue, K. Soejima, K. Yoshinaga, H. Kuma, N. Hamasaki

研究成果: ジャーナルへの寄稿記事

22 引用 (Scopus)

抄録

Magnetic immunoassays utilizing magnetic markers and a high-Tc SQUID have been performed. We first showed a design of the SQUID for the sensitive detection of the magnetic signal from the marker, where the spatial distribution of the signal field was taken into account. Using the design, we can obtain the relationship between the magnetization of the maker and the signal flux detected with the SQUID. This relationship is important for quantitative evaluation of the immunoassay. Next, we detected biological materials called IgE with a remanence measurement method, where a marker made of Fe3O4 particles with diameter of 25 nm was used. We showed that 2 atto-mol of IgE can be detected, which shows high sensitivity of the present method.

元の言語英語
ページ(範囲)660-663
ページ数4
ジャーナルIEEE Transactions on Applied Superconductivity
15
発行部数2 PART I
DOI
出版物ステータス出版済み - 6 1 2005

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immunoassay
SQUIDs
markers
Immunoglobulin E
magnetic signals
Remanence
remanence
Biological materials
Spatial distribution
Magnetization
spatial distribution
Fluxes
magnetization
evaluation
sensitivity

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Electrical and Electronic Engineering

これを引用

Enpuku, K., Inoue, K., Soejima, K., Yoshinaga, K., Kuma, H., & Hamasaki, N. (2005). Magnetic immunoassays utilizing magnetic markers and a high-TC SQUID. IEEE Transactions on Applied Superconductivity, 15(2 PART I), 660-663. https://doi.org/10.1109/TASC.2005.849991

Magnetic immunoassays utilizing magnetic markers and a high-TC SQUID. / Enpuku, K.; Inoue, K.; Soejima, K.; Yoshinaga, K.; Kuma, H.; Hamasaki, N.

:: IEEE Transactions on Applied Superconductivity, 巻 15, 番号 2 PART I, 01.06.2005, p. 660-663.

研究成果: ジャーナルへの寄稿記事

Enpuku, K, Inoue, K, Soejima, K, Yoshinaga, K, Kuma, H & Hamasaki, N 2005, 'Magnetic immunoassays utilizing magnetic markers and a high-TC SQUID', IEEE Transactions on Applied Superconductivity, 巻. 15, 番号 2 PART I, pp. 660-663. https://doi.org/10.1109/TASC.2005.849991
Enpuku, K. ; Inoue, K. ; Soejima, K. ; Yoshinaga, K. ; Kuma, H. ; Hamasaki, N. / Magnetic immunoassays utilizing magnetic markers and a high-TC SQUID. :: IEEE Transactions on Applied Superconductivity. 2005 ; 巻 15, 番号 2 PART I. pp. 660-663.
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