Magnetic resonance differentiation between T2 and T1 gallbladder carcinoma: Significance of subserosal enhancement on the delayed phase dynamic study

Kengo Yoshimitsu, Yunosuke Nishihara, Daisuke Okamoto, Yasuhiro Ushijima, Akihiro Nishie, Koji Yamaguchi, Akinobu Taketomi, Hiroshi Honda

研究成果: Contribution to journalArticle査読

8 被引用数 (Scopus)

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Purpose: The aim of this study is to investigate whether subserosal enhancement on the delayed-phase dynamic magnetic resonance (MR) study (SED) can differentiate T2 from T1 gallbladder carcinoma (GBC). Methods: The institutional research board approved this retrospective study. Between 1997 and 2006, there were surgically proven 11 T1 and 21 T2 GBC in 30 patients, all of whom had undergone preoperative contrast enhanced dynamic MR study, either with a 2D sequence (n=17) or 3D sequences (n=15). All images were reviewed by two radiologists for the presence of SED, and receiver operating characteristic (ROC) curve analysis was performed. Sensitivity, specificity, positive and negative predictive values were calculated by consensus. Results: The areas under the ROC curves of the two readers were 0.91 and 0.86, and the kappa value was 0.78. Of the 21 T2 GBC, 18 and 3 showed positive and negative SED, respectively. Of the 11 T1 GBC, 1 and 10 showed positive and negative SED, respectively. The sensitivity, specificity, positive and negative predictive values of SED for diagnosing T2 lesions were 86%, 88%, 91% and 77%, respectively. Conclusions: In conclusion, SED may be a useful sign to differentiate T2 from T1 GBC, which would affect the preoperative surgical planning of the patients.

本文言語英語
ページ(範囲)854-859
ページ数6
ジャーナルMagnetic Resonance Imaging
30
6
DOI
出版ステータス出版済み - 7 2012

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

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