TY - JOUR
T1 - Mammalian cell mutants of membrane phlospholipid biogenesis
AU - Nishijima, Masahiro
AU - Kuge, Osamu
AU - Hanada, Kentaro
PY - 1997/8
Y1 - 1997/8
N2 - Cultured mammalian cell mutants defective in the biosynthesis of membrane phospholipids, although limited in number, are increasing our understanding of the molecular mechanisms underlying the biogenesis and the biological significance of membrane phospholipids in higher eukaryotes. This review summarizes the progress in the isolation and characterization of such mutants, focusing on those isolated from cultured Chinese hamster ovary (CHO) cells.
AB - Cultured mammalian cell mutants defective in the biosynthesis of membrane phospholipids, although limited in number, are increasing our understanding of the molecular mechanisms underlying the biogenesis and the biological significance of membrane phospholipids in higher eukaryotes. This review summarizes the progress in the isolation and characterization of such mutants, focusing on those isolated from cultured Chinese hamster ovary (CHO) cells.
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U2 - 10.1016/S0962-8924(97)01084-2
DO - 10.1016/S0962-8924(97)01084-2
M3 - Review article
C2 - 17708968
AN - SCOPUS:0030807664
VL - 7
SP - 324
EP - 329
JO - Trends in Cell Biology
JF - Trends in Cell Biology
SN - 0962-8924
IS - 8
ER -