Measurement of cyclic microdeformation of arterial wall with pulsatile flow

Shigehiro Hashimoto, Shirou Manabe, Kazuhiro Ikegami, Yoshinori Murashige, Chiaki Miyamoto, Masayoshi Omori, Reiji Hattori, Hajime Otani, Hiroji Imamura

研究成果: Contribution to journalArticle査読


The cyclic micro-deformation of the arterial wall with pulsatile flow was measured to get fundamental data for estimation of the mechanical stress in endothelial cells. The descending aorta (1-2 mm diameter) of an anesthetized rat was exposed under thoracotomy. The displacement measuring system was assembled with the charge coupled devise (CCD) of laser sensor. The movement of laser beam (670 nm wave length) reflected at the vessel wall was calibrated to the movement of the arterial wall. The fluctuating movement was also measured at four points marked on the vessel wall with CCD camera to distinguish the circumferential movement from the longitudinal one. The results showed that the present designed system has enough resolution to measure the arterial vessel wall cyclic-micro-fluctuation, which is 10 percent of diameter in the circumferential direction without deformation in the longitudinal direction with the cardiac beating in vivo.

ジャーナルProceedings of SPIE - The International Society for Optical Engineering
出版ステータス出版済み - 6 14 2002

All Science Journal Classification (ASJC) codes

  • 電子材料、光学材料、および磁性材料
  • 凝縮系物理学
  • コンピュータ サイエンスの応用
  • 応用数学
  • 電子工学および電気工学


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