Mechanism of the lifespan extension of Caenorhabditis elegans by electrolyzed reduced water-participation of pt nanoparticles

Hanxu Yan, Tomoya Kinjo, Huaize Tian, Takeki Hamasaki, Kiichiro Teruya, Shigeru Kabayama, Sanetaka Shirahata

研究成果: ジャーナルへの寄稿記事

15 引用 (Scopus)

抄録

Electrolyzed reduced water (ERW) contains a large amount of molecular hydrogen and asmall amount of Pt nanoparticles (Pt NPs). We have found that ERW significantly extended the lifespan of Caenorhabditis elegans in a novel culture medium designated Water Medium.In this study, we found that synthetic Pt NPs at ppb levels significantly extended the nematode lifespan and scavenged reactive oxygen species (ROS) in the nematode induced by paraquat treatment. In contrast, a high concentration of dissolved molecular hydrogen had no significant effect on the lifespan of the nematode. These findings suggest that the Pt NPs in ERW, rather than the molecular hydrogen, extend the longevity of the nematode, at least partly by scavenging ROS.

元の言語英語
ページ(範囲)1295-1299
ページ数5
ジャーナルBioscience, Biotechnology and Biochemistry
75
発行部数7
DOI
出版物ステータス出版済み - 8 1 2011

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Caenorhabditis elegans
Nanoparticles
Hydrogen
Water
Reactive Oxygen Species
Paraquat
Scavenging
Culture Media

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

これを引用

Mechanism of the lifespan extension of Caenorhabditis elegans by electrolyzed reduced water-participation of pt nanoparticles. / Yan, Hanxu; Kinjo, Tomoya; Tian, Huaize; Hamasaki, Takeki; Teruya, Kiichiro; Kabayama, Shigeru; Shirahata, Sanetaka.

:: Bioscience, Biotechnology and Biochemistry, 巻 75, 番号 7, 01.08.2011, p. 1295-1299.

研究成果: ジャーナルへの寄稿記事

Yan, Hanxu ; Kinjo, Tomoya ; Tian, Huaize ; Hamasaki, Takeki ; Teruya, Kiichiro ; Kabayama, Shigeru ; Shirahata, Sanetaka. / Mechanism of the lifespan extension of Caenorhabditis elegans by electrolyzed reduced water-participation of pt nanoparticles. :: Bioscience, Biotechnology and Biochemistry. 2011 ; 巻 75, 番号 7. pp. 1295-1299.
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