抄録
Electrolyzed reduced water (ERW) contains a large amount of molecular hydrogen and asmall amount of Pt nanoparticles (Pt NPs). We have found that ERW significantly extended the lifespan of Caenorhabditis elegans in a novel culture medium designated Water Medium.In this study, we found that synthetic Pt NPs at ppb levels significantly extended the nematode lifespan and scavenged reactive oxygen species (ROS) in the nematode induced by paraquat treatment. In contrast, a high concentration of dissolved molecular hydrogen had no significant effect on the lifespan of the nematode. These findings suggest that the Pt NPs in ERW, rather than the molecular hydrogen, extend the longevity of the nematode, at least partly by scavenging ROS.
| 元の言語 | 英語 |
|---|---|
| ページ（範囲） | 1295-1299 |
| ページ数 | 5 |
| ジャーナル | Bioscience, Biotechnology and Biochemistry |
| 巻 | 75 |
| 発行部数 | 7 |
| DOI | |
| 出版物ステータス | 出版済み - 8 1 2011 |
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All Science Journal Classification (ASJC) codes
- Biotechnology
- Analytical Chemistry
- Biochemistry
- Applied Microbiology and Biotechnology
- Molecular Biology
- Organic Chemistry
これを引用
Mechanism of the lifespan extension of Caenorhabditis elegans by electrolyzed reduced water-participation of pt nanoparticles. / Yan, Hanxu; Kinjo, Tomoya; Tian, Huaize; Hamasaki, Takeki; Teruya, Kiichiro; Kabayama, Shigeru; Shirahata, Sanetaka.
：: Bioscience, Biotechnology and Biochemistry, 巻 75, 番号 7, 01.08.2011, p. 1295-1299.研究成果: ジャーナルへの寄稿 › 記事
}
TY - JOUR
T1 - Mechanism of the lifespan extension of Caenorhabditis elegans by electrolyzed reduced water-participation of pt nanoparticles
AU - Yan, Hanxu
AU - Kinjo, Tomoya
AU - Tian, Huaize
AU - Hamasaki, Takeki
AU - Teruya, Kiichiro
AU - Kabayama, Shigeru
AU - Shirahata, Sanetaka
PY - 2011/8/1
Y1 - 2011/8/1
N2 - Electrolyzed reduced water (ERW) contains a large amount of molecular hydrogen and asmall amount of Pt nanoparticles (Pt NPs). We have found that ERW significantly extended the lifespan of Caenorhabditis elegans in a novel culture medium designated Water Medium.In this study, we found that synthetic Pt NPs at ppb levels significantly extended the nematode lifespan and scavenged reactive oxygen species (ROS) in the nematode induced by paraquat treatment. In contrast, a high concentration of dissolved molecular hydrogen had no significant effect on the lifespan of the nematode. These findings suggest that the Pt NPs in ERW, rather than the molecular hydrogen, extend the longevity of the nematode, at least partly by scavenging ROS.
AB - Electrolyzed reduced water (ERW) contains a large amount of molecular hydrogen and asmall amount of Pt nanoparticles (Pt NPs). We have found that ERW significantly extended the lifespan of Caenorhabditis elegans in a novel culture medium designated Water Medium.In this study, we found that synthetic Pt NPs at ppb levels significantly extended the nematode lifespan and scavenged reactive oxygen species (ROS) in the nematode induced by paraquat treatment. In contrast, a high concentration of dissolved molecular hydrogen had no significant effect on the lifespan of the nematode. These findings suggest that the Pt NPs in ERW, rather than the molecular hydrogen, extend the longevity of the nematode, at least partly by scavenging ROS.
UR - http://www.scopus.com/inward/record.url?scp=79960785805&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79960785805&partnerID=8YFLogxK
U2 - 10.1271/bbb.110072
DO - 10.1271/bbb.110072
M3 - Article
C2 - 21737933
AN - SCOPUS:79960785805
VL - 75
SP - 1295
EP - 1299
JO - Bioscience, Biotechnology and Biochemistry
JF - Bioscience, Biotechnology and Biochemistry
SN - 0916-8451
IS - 7
ER -