Mechanisms underlying increased vascular smooth muscle contractility in the rabbit basilar artery following subarachnoid hemorrhage

Yuichiro Kikkawa, Katsuharu Kameda, Satoshi Matsuo, Ryota Kurogi, Akira Nakamizo, Masahiro Mizoguchi, Tomio Sasaki

研究成果: Contribution to journalArticle査読

抄録

Increased vascular contractility plays an important role in the development of cerebral vasospasm following subarachnoid hemorrhage (SAH). Here, we summarize our current knowledge regarding molecular mechanisms that contribute to increased smooth muscle contractility of rabbit basilar artery following SAH. Our studies demonstrated that upregulation of receptor expression, impairment of feedback regulation of receptor activity, and enhancement of myofilament Ca2+ sensitization might lead to increased smooth muscle contractility following SAH.

本文言語英語
ページ(範囲)95-98
ページ数4
ジャーナルActa Neurochirurgica, Supplementum
120
DOI
出版ステータス出版済み - 2015

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

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