Mechanisms underlying increased vascular smooth muscle contractility in the rabbit basilar artery following subarachnoid hemorrhage

Yuichiro Kikkawa, Katsuharu Kameda, Satoshi Matsuo, Ryota Kurogi, Akira Nakamizo, Masahiro Mizoguchi, Tomio Sasaki

研究成果: ジャーナルへの寄稿記事

抄録

Increased vascular contractility plays an important role in the development of cerebral vasospasm following subarachnoid hemorrhage (SAH). Here, we summarize our current knowledge regarding molecular mechanisms that contribute to increased smooth muscle contractility of rabbit basilar artery following SAH. Our studies demonstrated that upregulation of receptor expression, impairment of feedback regulation of receptor activity, and enhancement of myofilament Ca2+ sensitization might lead to increased smooth muscle contractility following SAH.

元の言語英語
ページ(範囲)95-98
ページ数4
ジャーナルActa Neurochirurgica, Supplementum
120
DOI
出版物ステータス出版済み - 1 1 2015

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Basilar Artery
Subarachnoid Hemorrhage
Vascular Smooth Muscle
Rabbits
Smooth Muscle
Intracranial Vasospasm
Myofibrils
Blood Vessels
Up-Regulation

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

これを引用

Mechanisms underlying increased vascular smooth muscle contractility in the rabbit basilar artery following subarachnoid hemorrhage. / Kikkawa, Yuichiro; Kameda, Katsuharu; Matsuo, Satoshi; Kurogi, Ryota; Nakamizo, Akira; Mizoguchi, Masahiro; Sasaki, Tomio.

:: Acta Neurochirurgica, Supplementum, 巻 120, 01.01.2015, p. 95-98.

研究成果: ジャーナルへの寄稿記事

Kikkawa, Yuichiro ; Kameda, Katsuharu ; Matsuo, Satoshi ; Kurogi, Ryota ; Nakamizo, Akira ; Mizoguchi, Masahiro ; Sasaki, Tomio. / Mechanisms underlying increased vascular smooth muscle contractility in the rabbit basilar artery following subarachnoid hemorrhage. :: Acta Neurochirurgica, Supplementum. 2015 ; 巻 120. pp. 95-98.
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