Mechanobiology of endothelial cells related to the pathogenesis of arterial disease

    研究成果: Chapter in Book/Report/Conference proceedingChapter

    抄録

    Arteriosclerosis occurs preferentially at the inner curvature of blood vessels where shear stress induced by blood flow is low. Endothelial cells, which line the inner surface of blood vessels, transport all substances from vessels to tissues. It is well known that many functions of endothelial cells are affected by fluid shear stress, and it has been hypothesized that the dysfunction of endothelial transport is related to arteriogenesis. Endothelial transport is divided into two primary types: paracellular transport, which is passive, and transcellular transport, which is active. In this chapter, we introduce these endothelial transport processes and discuss the ways they are influenced by various shear stress conditions.

    本文言語英語
    ホスト出版物のタイトルVascular Engineering
    ホスト出版物のサブタイトルNew Prospects of Vascular Medicine and Biology with a Multidiscipline Approach
    出版社Springer Japan
    ページ199-209
    ページ数11
    ISBN(電子版)9784431548010
    ISBN(印刷版)9784431548003
    DOI
    出版ステータス出版済み - 1 1 2016

    All Science Journal Classification (ASJC) codes

    • 医学(全般)
    • 生化学、遺伝学、分子生物学(全般)
    • 工学(全般)

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