Metabolic profiling and identification of the genetic varieties and agricultural origin of Cnidium officinale and Ligusticum chuanxiong

Shizu Kobayashi, Saki Nagasawa, Yutaka Yamamoto, Kang Donghyo, Takeshi Bamba, Eiichiro Fukusaki

研究成果: ジャーナルへの寄稿記事

11 引用 (Scopus)

抄録

Quality control methods for . Cnidium officinale and . Ligusticum chuanxiong are lacking because their quality is influenced by multiple factors. Thus, there is a need to develop a multifactorial method for measuring quality that is both standardized and practical. Here, we report a profiling method based on gas chromatography-mass spectrometry (GC-MS) to discriminate among the genetic varieties and agricultural origins of . C. officinale and . L. chuanxiong. Our metabolome analysis identified 68 metabolites, 13 of which were newly identified in our samples. The S-plot of the OPLS discriminant analysis enabled us to determine significant biomarkers. Using only double-compound biomarkers, the samples were successfully classified into distinct groups defined by genetic variety and cultivation origin. This method will simplify the process of searching for quality control markers that can be used to determine genetic variety and agricultural origin.

元の言語英語
ページ(範囲)86-91
ページ数6
ジャーナルJournal of Bioscience and Bioengineering
114
発行部数1
DOI
出版物ステータス出版済み - 7 1 2012
外部発表Yes

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Cnidium
Ligusticum
Biomarkers
Quality control
Discriminant analysis
Metabolites
Quality Control
Gas chromatography
Mass spectrometry
Metabolome
Discriminant Analysis
Gas Chromatography-Mass Spectrometry

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology

これを引用

Metabolic profiling and identification of the genetic varieties and agricultural origin of Cnidium officinale and Ligusticum chuanxiong. / Kobayashi, Shizu; Nagasawa, Saki; Yamamoto, Yutaka; Donghyo, Kang; Bamba, Takeshi; Fukusaki, Eiichiro.

:: Journal of Bioscience and Bioengineering, 巻 114, 番号 1, 01.07.2012, p. 86-91.

研究成果: ジャーナルへの寄稿記事

Kobayashi, Shizu ; Nagasawa, Saki ; Yamamoto, Yutaka ; Donghyo, Kang ; Bamba, Takeshi ; Fukusaki, Eiichiro. / Metabolic profiling and identification of the genetic varieties and agricultural origin of Cnidium officinale and Ligusticum chuanxiong. :: Journal of Bioscience and Bioengineering. 2012 ; 巻 114, 番号 1. pp. 86-91.
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