Method for a convenient and efficient synthesis of amino acid acrylic monomers with zwitterionic structure

Shoji Nagaoka, Atsuomi Shundo, Takao Satoh, Kazuhiko Nagira, Ryoich Kishi, Katsuhiko Ueno, Kokoro Iio, Hirotaka Ihara

研究成果: ジャーナルへの寄稿記事

22 引用 (Scopus)

抜粋

Ampholyte monomers with zwitterionic moiety derived from α-amino acid, that is, L-lysine and L-serine, were obtained using a method in which their copper complexes could be produced in simple steps. The N-acryloylation of L-lysine and L-serine was carried out by reaction between their copper complexes and acryloyl chloride. Specifically, the removal of copper from the copper complex of acryloyl amino acid through the use of 8-hydroxyquinoline as an organic chelate precipitant increased the yield of the ampholyte monomers with zwitterionic moiety. These syntheses were easily carried out in a three-step procedure.

元の言語英語
ページ(範囲)2529-2534
ページ数6
ジャーナルSynthetic Communications
35
発行部数19
DOI
出版物ステータス出版済み - 10 12 2005
外部発表Yes

    フィンガープリント

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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