Methylobamine, a UVA-absorbing compound from the plant-associated bacteria methylobacterium sp.

Tsunashi Kamo, Syuntaro Hiradate, Ken Suzuki, Ichiro Fujita, Shinji Yamaki, Tadashi Yoneda, Motoo Koitabashi, Shigenobu Yoshida

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

抄録

To survive in harsh environments, phyllosphere microorganisms have developed numerous adaptive strategies against stressors. One such strategy is the synthesis of compounds that absorb ultraviolet A radiation (UVA). The chemical structure of a UVA-absorbing compound from Methylobacterium sp. strain W-213 was elucidated by spectroscopic analyses. 1H, 13C, and two-dimensional nuclear magnetic resonance spectra indicated the presence of N-methyl-α-galactosamine. The entire structure was revealed by interpretation of INADEQUATE and high-resolution liquid chromatography/electrospray ionization mass spectra. The absolute configuration was established by X-ray analysis and the compound was identified as 2-((4aR,6R,7R,8R,8aR)-7,8-dihydroxy-6-hydroxymethyl-1,2-dimethyl-4aH,6H,7H,8H,8aH-pyrano[2,3-b][1,4]oxazin-3-yl)-2-iminoacetic acid and named ‘methylobamine’. Methylobamine shows promise for pharmaceutical and cosmetic applications due to its high polarity, UVA absorption properties, and stability under UVA exposure.

元の言語英語
ページ(範囲)141-143
ページ数3
ジャーナルNatural Product Communications
13
発行部数2
出版物ステータス出版済み - 1 1 2018

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Methylobacterium
ultraviolet radiation
Radiation
Bacteria
Galactosamine
bacteria
Cosmetics
Liquid Chromatography
Magnetic Resonance Spectroscopy
X-Rays
phyllosphere
galactosamine
Acids
cosmetics
chemical structure
Pharmaceutical Preparations
ionization
liquid chromatography
nuclear magnetic resonance spectroscopy
X-radiation

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery
  • Plant Science
  • Complementary and alternative medicine

これを引用

Kamo, T., Hiradate, S., Suzuki, K., Fujita, I., Yamaki, S., Yoneda, T., ... Yoshida, S. (2018). Methylobamine, a UVA-absorbing compound from the plant-associated bacteria methylobacterium sp. Natural Product Communications, 13(2), 141-143.

Methylobamine, a UVA-absorbing compound from the plant-associated bacteria methylobacterium sp. / Kamo, Tsunashi; Hiradate, Syuntaro; Suzuki, Ken; Fujita, Ichiro; Yamaki, Shinji; Yoneda, Tadashi; Koitabashi, Motoo; Yoshida, Shigenobu.

:: Natural Product Communications, 巻 13, 番号 2, 01.01.2018, p. 141-143.

研究成果: ジャーナルへの寄稿記事

Kamo, T, Hiradate, S, Suzuki, K, Fujita, I, Yamaki, S, Yoneda, T, Koitabashi, M & Yoshida, S 2018, 'Methylobamine, a UVA-absorbing compound from the plant-associated bacteria methylobacterium sp.', Natural Product Communications, 巻. 13, 番号 2, pp. 141-143.
Kamo, Tsunashi ; Hiradate, Syuntaro ; Suzuki, Ken ; Fujita, Ichiro ; Yamaki, Shinji ; Yoneda, Tadashi ; Koitabashi, Motoo ; Yoshida, Shigenobu. / Methylobamine, a UVA-absorbing compound from the plant-associated bacteria methylobacterium sp. :: Natural Product Communications. 2018 ; 巻 13, 番号 2. pp. 141-143.
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