Microchip-based immunoassay, which is immunoassay performed on a microchip, has recently been used in various fields owing to its advantages, such as reduction in sample and reagent consumption, short analysis time and simple operation. Different types of immunoassay have been applied to the miniaturization on a microchip. Material and surface modifications of a microchip, introducing and moving samples and detection must be taken into consideration in order to realize a microchip-based immunoassay. Also, the microchip system should be designed according to a type of immunoassay. In the present review article, we explain the types and classifications of immunoassays and describe important points for developing a microchip-based immunoassay. We then introduce several examples of microchip-based immunoassay.
All Science Journal Classification (ASJC) codes
- Analytical Chemistry