Microfluidic rare cancer cell collection with anti-EpCAM antibody modified euglena by phototaxis inside microchannels

Yukihiro Okamoto, Yukinori Nakakita, Takahiro Sano, Noritada Kaji, Manabu Tokeshi, Yoshinobu Baba

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

抄録

We develop a microfluidic cell separation method which combined microfluidic devices and multifunctional Euglena. Multifunctional Euglena for cell separation was successfully prepared by the surface modification of Euglena cell membrane and its performances were confirmed. Mutlifunctional Euglena in the inlet attached cells, migrated inside the microchannel by phototaxis towards the outlet chamber, and brought specific cells to the outlet. After moving to the outlet, cells in the outlet were detached from Euglena. Since it is based on the unique characters of Euglena, our method needs only simple device and can deal with small to large amount variety kinds of samples including cells.

本文言語英語
ホスト出版物のタイトルProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
出版社Chemical and Biological Microsystems Society
ページ1108-1110
ページ数3
ISBN(印刷版)9780979806452
出版ステータス出版済み - 1 1 2012
外部発表はい
イベント16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 - Okinawa, 日本
継続期間: 10 28 201211 1 2012

出版物シリーズ

名前Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012

その他

その他16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
国/地域日本
CityOkinawa
Period10/28/1211/1/12

All Science Journal Classification (ASJC) codes

  • 化学工学(その他)
  • バイオエンジニアリング

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