TY - JOUR
T1 - Microglia
T2 - A Unique Versatile Cell in the Central Nervous System
AU - Masuda, Takahiro
AU - Prinz, Marco
PY - 2016/4/20
Y1 - 2016/4/20
N2 - Microglia are the resident monocytic cells in the central nervous system (CNS), where they constitute the complex tissue structure together with a diverse set of cell-types, including neurons, glial cells, and vasculature. Different from other cells, microglia have distinct features, including not only their origin but functions in the CNS, and serve multiple roles within healthy and diseased CNS tissue. The present review highlights the latest advance in our understanding of the nature of microglia in the CNS, from their origin to both the physiological and pathological roles throughout their whole life.
AB - Microglia are the resident monocytic cells in the central nervous system (CNS), where they constitute the complex tissue structure together with a diverse set of cell-types, including neurons, glial cells, and vasculature. Different from other cells, microglia have distinct features, including not only their origin but functions in the CNS, and serve multiple roles within healthy and diseased CNS tissue. The present review highlights the latest advance in our understanding of the nature of microglia in the CNS, from their origin to both the physiological and pathological roles throughout their whole life.
UR - http://www.scopus.com/inward/record.url?scp=84966280571&partnerID=8YFLogxK
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U2 - 10.1021/acschemneuro.5b00317
DO - 10.1021/acschemneuro.5b00317
M3 - Review article
C2 - 26844374
AN - SCOPUS:84966280571
VL - 7
SP - 428
EP - 434
JO - ACS Chemical Neuroscience
JF - ACS Chemical Neuroscience
SN - 1948-7193
IS - 4
ER -