Mitochondria and antiviral innate immunity

Takumi Koshiba, Nasir Bashiruddin, Shunichiro Kawabata

研究成果: ジャーナルへの寄稿評論記事

18 引用 (Scopus)

抄録

Mitochondria, dynamic organelles that undergo continuous cycles of fusion and fission, are the powerhouses of eukaryotic cells. Recent research indicates that mitochondria also act as platforms for antiviral immunity in vertebrates. Mitochondrial-mediated antiviral immunity depends on activation of the retinoic acid-inducible gene I (RIG-I)-like receptors signal transduction pathway and the participation of the mitochondrial outer membrane adaptor protein "mitochondrial antiviral signaling (MAVS)". Here we discuss recent findings that suggest how mitochondria contribute to antiviral innate immunity.

元の言語英語
ページ(範囲)257-262
ページ数6
ジャーナルInternational Journal of Biochemistry and Molecular Biology
2
発行部数3
出版物ステータス出版済み - 12 1 2011

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Mitochondria
Innate Immunity
Antiviral Agents
Immunity
Signal transduction
Mitochondrial Proteins
Eukaryotic Cells
Tretinoin
Organelles
Vertebrates
Signal Transduction
Membrane Proteins
Fusion reactions
Genes
Chemical activation
Membranes
Research

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology

これを引用

Mitochondria and antiviral innate immunity. / Koshiba, Takumi; Bashiruddin, Nasir; Kawabata, Shunichiro.

:: International Journal of Biochemistry and Molecular Biology, 巻 2, 番号 3, 01.12.2011, p. 257-262.

研究成果: ジャーナルへの寄稿評論記事

Koshiba, Takumi ; Bashiruddin, Nasir ; Kawabata, Shunichiro. / Mitochondria and antiviral innate immunity. :: International Journal of Biochemistry and Molecular Biology. 2011 ; 巻 2, 番号 3. pp. 257-262.
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