Mitochondria and antiviral innate immunity

Takumi Koshiba, Nasir Bashiruddin, Shunichiro Kawabata

研究成果: Contribution to journalReview article査読

21 被引用数 (Scopus)

抄録

Mitochondria, dynamic organelles that undergo continuous cycles of fusion and fission, are the powerhouses of eukaryotic cells. Recent research indicates that mitochondria also act as platforms for antiviral immunity in vertebrates. Mitochondrial-mediated antiviral immunity depends on activation of the retinoic acid-inducible gene I (RIG-I)-like receptors signal transduction pathway and the participation of the mitochondrial outer membrane adaptor protein "mitochondrial antiviral signaling (MAVS)". Here we discuss recent findings that suggest how mitochondria contribute to antiviral innate immunity.

本文言語英語
ページ(範囲)257-262
ページ数6
ジャーナルInternational Journal of Biochemistry and Molecular Biology
2
3
出版ステータス出版済み - 12 1 2011

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology

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