Mitochondrial physiology and cerebrospinal protection

Morika Suzuki, Hiroki Kato, Naomi Hachiya

研究成果: Chapter in Book/Report/Conference proceedingChapter

抄録

Mitochondria maintain their numbers by the fusion and fission of preexisting mitochondria. Continuous mitochondrial fusion mixes the compartments, whereas fission segregates morphologically and functionally damaged mitochondria. This changing of their shape allows mitochondria to control the life and death processes of cells, such as apoptosis, the maintenance of cellular homeostasis, and ultimately the processes that occur in neurological disorders and metabolic diseases. GTPase family proteins and their regulators modulate the fusion/fission events, and a type of autophagy known as mitophagy removes damaged mitochondria. Although the molecular mechanistic effects of anesthetics on mitochondria are not yet clear, an enhanced understanding of this knowledge will be useful for the establishment of therapeutic approaches.

本文言語英語
ホスト出版物のタイトルNeuroanesthesia and Cerebrospinal Protection
出版社Springer Japan
ページ63-70
ページ数8
ISBN(電子版)9784431544906
ISBN(印刷版)9784431544890
DOI
出版ステータス出版済み - 8 7 2015
外部発表はい

All Science Journal Classification (ASJC) codes

  • Medicine(all)

フィンガープリント 「Mitochondrial physiology and cerebrospinal protection」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル