Mitogenic properties of pokeweed lectin-D isoforms on human peripheral blood lymphocytes: Non-mitogen PL-D1 and mitogen PL-D2

Kenichi Yamaguchi, Mizuki Uechi, Yoshinori Katakura, Tatsuya Oda, Masatsune Ishiguro

研究成果: ジャーナルへの寄稿記事

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We investigated native structures and mitogenic properties of pokeweed lectin-D isoforms (PL-D1 and -D2) on human peripheral blood lymphocytes along with other isolectins (PL-A to -C). Both native PL-D isoforms appeared to behave as monomers. PL-D2 proliferated the lymphocytes like PL-C, whereas PL-D1 had no mitogenicity. PL-D1 acquired mitogenic activity after trimming of the C-terminal dipeptide.

元の言語英語
ページ(範囲)1591-1593
ページ数3
ジャーナルBioscience, Biotechnology and Biochemistry
68
発行部数7
DOI
出版物ステータス出版済み - 7 1 2004

    フィンガープリント

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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