Mixed La-Li heterobimetallic complexes for tertiary nitroaldol resolution

Shin Ya Tosaki, Keiichi Hara, Vijay Gnanadesikan, Hiroyuki Morimoto, Shinji Harada, Mari Sugita, Noriyuki Yamagiwa, Shigeki Matsunaga, Masakatsu Shibasaki

研究成果: ジャーナルへの寄稿記事

92 引用 (Scopus)

抜粋

A kinetic resolution of tertiary nitroaldols derived from simple ketones is described. Mixed BINOL/biphenol La-Li heterobimetallic complexes gave the best selectivity in retro-nitroaldol reactions of racemic tertiary nitroaldols. By using a mixture of La-Li3-(1a)3 complex (LLB 2a) and La-Li3-(1b)3 (LLB* 2b) complex in a ratio of 2/1, chiral tertiary nitroaldols were obtained in 80-97% ee and 30-47% recovery yield.

元の言語英語
ページ(範囲)11776-11777
ページ数2
ジャーナルJournal of the American Chemical Society
128
発行部数36
DOI
出版物ステータス出版済み - 9 13 2006
外部発表Yes

    フィンガープリント

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

これを引用

Tosaki, S. Y., Hara, K., Gnanadesikan, V., Morimoto, H., Harada, S., Sugita, M., ... Shibasaki, M. (2006). Mixed La-Li heterobimetallic complexes for tertiary nitroaldol resolution. Journal of the American Chemical Society, 128(36), 11776-11777. https://doi.org/10.1021/ja064858l