Modulation of cytotoxic effect of anticancer drugs by dipyridamole in HeLa cells in vitro

H. Kusumoto, Yoshihiko Maehara, Y. Sakaguchi, S. Kohnoe, R. Kumashiro, K. Sugimachi

研究成果: Contribution to journalArticle査読

4 被引用数 (Scopus)

抄録

Exponentially growing HeLa cells were treated with various antitumor drugs and dipyridamole (DP), and the cell growth inhibition ratio was determined. Enhanced growth inhibition was found in combined treatment with DP and 5-fluorouracil, 1-hexylcarbamoyl-5-fluorouracil, methotrexate, adriamycin, daunomycin, 4'-0-tetrahydropyranyladriamycin, actinomycin D and vincristine. In contrast, reduction of the cytotoxic effect of cytosine arabinoside and enocitabine was found when these were combined with DP.

本文言語英語
ページ(範囲)1643-1645
ページ数3
ジャーナルAnticancer research
10
6
出版ステータス出版済み - 12 1 1990

All Science Journal Classification (ASJC) codes

  • 腫瘍学
  • 癌研究

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