Molecular orientation in the peptide self-assembled monolayers

Katsuhiko Fujita, Ryuichi Yokoyama, Tetsuo Tsutsui

研究成果: ジャーナルへの寄稿会議記事査読

1 被引用数 (Scopus)

抄録

Self-assembled monolayer (SAM) of peptides is investigated in terms of the correlation of their molecular orientation and the dipolar interactions. The used helical peptides containing a disulfide group on the terminal, which can form SAMs on a gold substrate, were synthesized. The molecular orientation was estimated from the reflection absorption IR intensity ratio of amide I and amide II bands which have transition moment almost parallel and perpendicular to the molecular axis, respectively. The adsorption behavior and layer thickness were determined by surface plasmon resonance. The molecular orientation depended on the dipolar interaction between the peptide molecules and between the peptide dipole and its image. The molecular direction against the substrate affects the orientation probably due to the interaction between the peptide dipole and Au-S polarization. This speculation is supported by the fact that the orientation difference by the molecular direction became smaller when the spacer from the helix body to the disulfide group is longer. The results indicate that the careful molecular design and optimal preparation condition of SAMs allow formation of well-organized and predetermined structure of nano-architecture even by use of large and complex molecules.

本文言語英語
ページ(範囲)P6241-P6246
ジャーナルMaterials Research Society Symposium - Proceedings
648
出版ステータス出版済み - 2001
イベントGrowth, Evolution and Properties of Surfaces, Thin Films and Self-Organized Strutures - Boston, MA, 米国
継続期間: 11月 27 200012月 1 2000

!!!All Science Journal Classification (ASJC) codes

  • 材料科学(全般)
  • 凝縮系物理学
  • 材料力学
  • 機械工学

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