Molecular recognition in a supramolecular hydrogel to afford a semi-wet sensor chip

Ibuki Yoshimura, Yoshifumi Miyahara, Noriyuki Kasagi, Hiroki Yamane, Akio Ojida, Itaru Hamachi

研究成果: Contribution to journalArticle査読

176 被引用数 (Scopus)

抄録

This communication describes a new molecular recognition chip using a semi-wet microenvironment provided by a self-assembled hydrogel. On the basis of the evidence that the molecular recognition capability of artificial chemosensors are practically retained even in the hydrogel compared to those in aqueous solution, we miniaturized the functionalized hydrogel to produce an unprecedented molecular recognition chip. We believe that the present noncovalent immobilization method is generally applicable to many chemosensors, which leads to a unique semi-wet sensor chip suitable to convenient and high-throughput assay to plural analytes.

本文言語英語
ページ(範囲)12204-12205
ページ数2
ジャーナルJournal of the American Chemical Society
126
39
DOI
出版ステータス出版済み - 10 6 2004

All Science Journal Classification (ASJC) codes

  • 触媒
  • 化学 (全般)
  • 生化学
  • コロイド化学および表面化学

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