Moyamoya syndrome with spherocytosis: Effect of splenectomy on strokes

Yoichi Tokunaga, Shouichi Ohga, Sachiyo Suita, Toshio Matsushima, Toshiro Hara

研究成果: ジャーナルへの寄稿記事

20 引用 (Scopus)

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A 3-year-old male patient with hereditary spherocytosis who developed moyamoya syndrome, presenting hemiplegia, and slurred speech is reported. Transient ischemic attacks occurred repeatedly with hemolytic crises. Magnetic resonance imaging and angiography revealed bilateral occlusion of the internal carotid and middle cerebral arteries with the formation of moyamoya vessels and multiple infarctions in the basal ganglia. Although splenectomy can increase the risk of stroke, no stroke occurred after splenectomy. On aspirin and dipyridamole therapy the patient has been free of neurologic deficits and progression of the vasculopathy for 5 years. This rare observation suggests that anemic hypoxia more greatly contributes to the progression of moyamoya syndrome than postsplenectomy thrombocytosis or reduced deformability of spherocytes.

元の言語英語
ページ(範囲)75-77
ページ数3
ジャーナルPediatric Neurology
25
発行部数1
DOI
出版物ステータス出版済み - 8 20 2001

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All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Neurology
  • Developmental Neuroscience
  • Clinical Neurology

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