Mucinous cystadenoma in the upper lip: Report of two cases

Tomohiro Yamada, Mayu Takahashi, Manabu Matsumoto, Makoto Toi, Seiji Ohno, Naoya Kitamura, Eri Sasabe, Tetsuya Yamamoto

研究成果: Contribution to journalArticle査読

2 被引用数 (Scopus)


Mucinous cystadenoma of the salivary gland is a very rare disease, and only a few cases have been reported. We report here 2 cases of mucinous cystadenoma in the upper lip. The first case was a 57-year-old man and the second was a 42-year-old woman. The tumors were painless nodules with a smooth-surfaced mucosa, and surgical excisions were performed. Histologically, the tumors were surrounded by a fibrous capsule and were composed of multiple cysts lined with columnar epithelial cells. The tumor cells contain mucous substances that reacted with periodic acid-Schiff base and Alcian blue. Immunohistochemical staining reveal ed that the tumor cells expressed cytokeratin (AE1/3 and CK7), but their immunoreactivity with MIB-1 (Ki-67) was less than 3%. They had negative immunoreactivity for neuroectoderm markers, S-100 protein, and myoepithelial markers, p63, α-smooth muscle actin, and calponin, except for the accompanying myoepithelial-like cells. No recurrences were noted after surgery at 7 years and 1 year, respectively.

ジャーナルInternational Journal of Surgical Pathology
出版ステータス出版済み - 6 2014

All Science Journal Classification (ASJC) codes

  • 解剖学
  • 外科
  • 病理学および法医学


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