TY - JOUR
T1 - Mucoepidermoid carcinoma of the liver
T2 - Report of a rare case and review of the literature
AU - Arakawa, Yusuke
AU - Shimada, Mitsuo
AU - Ikegami, Toru
AU - Kubo, Takayuki
AU - Imura, Satoru
AU - Morine, Yuji
AU - Kanemura, Hirofumi
AU - Mori, Hiroki
PY - 2008/7/1
Y1 - 2008/7/1
N2 - Although a mucoepidermoid carcinoma is sometimes seen as a neoplasm originating from the salivary glands, its origination from the liver is rare. A review of the medical literature in the English language disclosed only 16 cases originating from the hepatic system. The case explored here is that of an 81-year-old female, without any significant medical history, who was referred to our hospital for elevated liver function tests. Computed tomography (CT) showed a huge tumor, 10cm in diameter, in the right lobe of the liver. The central part of the tumor was consistently un-enhanced, suggesting a large necrotic area. The liver tumor was diagnosed as mucoepidermoid carcinoma by a percutaneous biopsy. Despite chemotherapy with radiation therapy, the tumor showed very aggressive malignancy, resulting in early mortality. We herein report on a rare case of primary mucoepidermoid carcinoma of the liver with pulmonary and lymph node metastasis, confirmed by autopsy, and review the literature.
AB - Although a mucoepidermoid carcinoma is sometimes seen as a neoplasm originating from the salivary glands, its origination from the liver is rare. A review of the medical literature in the English language disclosed only 16 cases originating from the hepatic system. The case explored here is that of an 81-year-old female, without any significant medical history, who was referred to our hospital for elevated liver function tests. Computed tomography (CT) showed a huge tumor, 10cm in diameter, in the right lobe of the liver. The central part of the tumor was consistently un-enhanced, suggesting a large necrotic area. The liver tumor was diagnosed as mucoepidermoid carcinoma by a percutaneous biopsy. Despite chemotherapy with radiation therapy, the tumor showed very aggressive malignancy, resulting in early mortality. We herein report on a rare case of primary mucoepidermoid carcinoma of the liver with pulmonary and lymph node metastasis, confirmed by autopsy, and review the literature.
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U2 - 10.1111/j.1872-034X.2008.00335.x
DO - 10.1111/j.1872-034X.2008.00335.x
M3 - Article
C2 - 18336545
AN - SCOPUS:44649099606
VL - 38
SP - 736
EP - 742
JO - Hepatology Research
JF - Hepatology Research
SN - 1386-6346
IS - 7
ER -