Multichannel biosensing platform of surface-immobilized gold nanospheres for linear and nonlinear optical imaging

Kazuma Tsuboi, Shinya Fukuba, Ryo Naraoka, Katsuhiko Fujita, Kotaro Kajikawa

研究成果: Contribution to journalArticle査読

15 被引用数 (Scopus)

抄録

What we believe to be a new label-free multichannel biosensing platform is proposed. It is composed of surface-immobilized gold nanospheres (SIGNs) above a gold surface with a nanogap supported by a merocyanine self-assembled monolayer. The circular SIGN spots with a diameter of 120 μm were arrayed for multichannel biosensing on a glass slide. Two kinds of sensing methods were examined: One is a reflectivity measurement of a blue ray and the other is a second-harmonic generation measurement. It was found that the SIGN system can be used as a promising platform for multichannel biosensing in both sensing methods.

本文言語英語
ページ(範囲)4486-4490
ページ数5
ジャーナルApplied Optics
46
20
DOI
出版ステータス出版済み - 7 10 2007

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics
  • Engineering (miscellaneous)
  • Electrical and Electronic Engineering

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